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dc.contributor.authorRyan, Victoria
dc.contributor.authorBrown, Hazel
dc.contributor.authorMinns Lowe, Catherine
dc.contributor.authorLewis, Jeremy
dc.date.accessioned2017-01-13T11:10:46Z
dc.date.available2017-01-13T11:10:46Z
dc.date.issued2016-08-15
dc.identifier.citationRyan , V , Brown , H , Minns Lowe , C & Lewis , J 2016 , ' The pathophysiology associated with primary (idiopathic) frozen shoulder: A systematic review ' , BMC Musculoskeletal Disorders , vol. 17 , no. 340 , pp. 1-21 . https://doi.org/10.1186/s12891-016-1190-9
dc.identifier.issn1471-2474
dc.identifier.otherPURE: 10547604
dc.identifier.otherPURE UUID: 7bbf2642-09ea-4a50-b355-e41c491eceac
dc.identifier.otherScopus: 84982084156
dc.identifier.urihttp://hdl.handle.net/2299/17510
dc.description© 2016 The Author(s). Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
dc.description.abstractAbstract Background Frozen shoulder is a common yet poorly understood musculoskeletal condition, which for many, is associated with substantial and protracted morbidity. Understanding the pathology associated with this condition may help to improve management. To date this has not been presented in a systematic fashion. As such, the aim of this review was to summarise the pathological changes associated with this primary frozen shoulder. Methods Databases: Medline, Embase, CINAHL, AMED, BNI and the Cochrane Library, were searched from inception to 2nd May, 2014. To be included participants must not have undergone any prior intervention. Two reviewers independently conducted the; searches, screening, data extraction and assessment of Risk of Bias using the Cochrane Risk of Bias Assessment Tool for non-Randomised Studies of Interventions (ACROBAT-NRSI). Only English language publications reporting findings in humans were included. The findings were summarised in narrative format. Results Thirteen observational studies (involving 417 shoulders) were included in the review. Eight studies reported magnetic resonance imaging or arthrography findings and 5 recorded histological findings. When reported mean ages of the participants ranged from 40.0 to 59.8 years. Duration of symptoms ranged from 0 to 30 months. The majority of studies (n = 7) were assessed to be of moderate risk of bias, two studies at high risk and the remaining four were rated as low risk of bias. Study characteristics were poorly reported and there was widespread variety observed between studies in respect of data collection methods and inclusion criteria employed. Pathological changes in the anterior shoulder joint capsule and related structures were commonly reported. Imaging identified pathological changes occurring in the coracohumeral ligament, axillary fold and rotator interval. Obliteration of the subcoracoid fat triangle also appeared to be pathognomonic. Histological studies were inconclusive but suggested that immune, inflammatory and fibrotic changes where associated with primary frozen shoulder. Conclusions This systematic review presents a summary of what is currently known about the tissue pathophysiology of primary frozen shoulder. Further studies that use standardised inclusion and exclusion criteria and investigate changes in naïve tissue at different stages of the condition are required.en
dc.format.extent22
dc.language.isoeng
dc.relation.ispartofBMC Musculoskeletal Disorders
dc.subjectFrozen Shoulder, Adhesive capsulitis, Systematic review, Imaging, Histology
dc.titleThe pathophysiology associated with primary (idiopathic) frozen shoulder: A systematic reviewen
dc.contributor.institutionSchool of Health and Social Work
dc.contributor.institutionDepartment of Allied Health Professions, Midwifery and Social Work
dc.contributor.institutionDepartment of Allied Health Professions and Midwifery
dc.contributor.institutionPhysiotherapy
dc.description.statusPeer reviewed
rioxxterms.versionVoR
rioxxterms.versionofrecordhttps://doi.org/10.1186/s12891-016-1190-9
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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