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dc.contributor.authorAmlôt, Richard
dc.contributor.authorCarter, Holly
dc.contributor.authorRiddle, Lorna
dc.contributor.authorLarner, Joanne
dc.contributor.authorChilcott, Robert P.
dc.date.accessioned2017-07-18T15:40:34Z
dc.date.available2017-07-18T15:40:34Z
dc.date.issued2017-06-16
dc.identifier.citationAmlôt , R , Carter , H , Riddle , L , Larner , J & Chilcott , R P 2017 , ' Volunteer trials of a novel improvised dry decontamination protocol for use during mass casualty incidents as part of the UK’S Initial Operational Response (IOR) ' , PLoS ONE , vol. 12 , no. 6 , e0179309 . https://doi.org/10.1371/journal.pone.0179309
dc.identifier.issn1932-6203
dc.identifier.urihttp://hdl.handle.net/2299/18985
dc.descriptionCopyright: © 2017 Amloˆt et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
dc.description.abstractPrevious studies have demonstrated that rapid evacuation, disrobing and emergency decontamination can enhance the ability of emergency services and acute hospitals to effectively manage chemically-contaminated casualties. The purpose of this human volunteer study was to further optimise such an “Initial Operational Response” by (1) identifying an appropriate method for performing improvised skin decontamination and (2) providing guidance for use by first responders and casualties. The study was performed using two readily available, absorbent materials (paper towels and incontinence pads). The decontamination effectiveness of the test materials was measured by quantifying the amount of a chemical warfare agent simulant (methyl salicylate) removed from each volunteer’s forearm skin. Results from the first study demonstrated that simulant recovery was lower in all of the dry decontamination conditions when compared to matched controls, suggesting that dry decontamination serves to reduce chemical exposure. Blotting in combination with rubbing was the most effective form of decontamination. There was no difference in effectiveness between the two absorbent materials. In the following study, volunteers performed improvised dry decontamination, either with or without draft guidelines. Volunteers who received the guidance were able to carry out improvised dry decontamination more effectively, using more of the absorbent product (blue roll) to ensure that all areas of the body were decontaminated and avoiding cross-contamination of other body areas by working systematically from the head downwards. Collectively, these two studies suggest that absorbent products that are available on ambulances and in acute healthcare settings may have generic applicability for improvised dry decontamination. Wherever possible, emergency responders and healthcare workers should guide casualties through decontamination steps; in the absence of explicit guidance and instructions, improvised dry decontamination may not be performed correctly or safely.en
dc.format.extent14026092
dc.language.isoeng
dc.relation.ispartofPLoS ONE
dc.subjectMedicine(all)
dc.subjectBiochemistry, Genetics and Molecular Biology(all)
dc.subjectAgricultural and Biological Sciences(all)
dc.titleVolunteer trials of a novel improvised dry decontamination protocol for use during mass casualty incidents as part of the UK’S Initial Operational Response (IOR)en
dc.contributor.institutionCentre for Research into Topical Drug Delivery and Toxicology
dc.contributor.institutionUniversity of Hertfordshire
dc.contributor.institutionCentre for Applied Clinical, Health and Care Research (CACHE)
dc.contributor.institutionToxicology
dc.contributor.institutionDepartment of Clinical, Pharmaceutical and Biological Science
dc.contributor.institutionPharmaceutics
dc.contributor.institutionSchool of Life and Medical Sciences
dc.description.statusPeer reviewed
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85020868202&partnerID=8YFLogxK
rioxxterms.versionofrecord10.1371/journal.pone.0179309
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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