dc.contributor.author | Cook, Michael | |
dc.contributor.author | Filippov, Sergey K | |
dc.contributor.author | Khutoryanskiy, Vitaliy V. | |
dc.date.accessioned | 2018-01-30T22:21:05Z | |
dc.date.available | 2018-01-30T22:21:05Z | |
dc.date.issued | 2017-08-31 | |
dc.identifier.citation | Cook , M , Filippov , S K & Khutoryanskiy , V V 2017 , ' Synthesis and solution properties of a temperature-responsive PNIPAM–b-PDMS–b-PNIPAM triblock copolymer ' , Colloid and Polymer Science , vol. 295 , no. 8 , pp. 1351-1358 . https://doi.org/10.1007/s00396-017-4084-y | |
dc.identifier.issn | 0303-402X | |
dc.identifier.other | PURE: 11395466 | |
dc.identifier.other | PURE UUID: b3bdf1ef-cb53-4d32-9acb-1dfdff14e76f | |
dc.identifier.other | Scopus: 85017160871 | |
dc.identifier.uri | http://hdl.handle.net/2299/19649 | |
dc.description | This document is the Accepted Manuscript version of the following article: Michael T. Cook, Sergey K. Filippov, and Vitaliy V. Khutoryanskiy, Synthesis and solution properties of a temperature-responsive PNIPAM–b-PDMS–b-PNIPAM triblock copolymer', Colloid and Polymer Science, (2017). Under embargo. Embargo end date: 5 April 2018. The version of record is available online at doi: 10.1007/s00396-017-4084-y. © Springer-Verlag Berlin Heidelberg 2017 | |
dc.description.abstract | In this paper, we report the synthesis and self-assembly of a novel thermoresponsive PNIPAM60–b-PDMS70–b-PNIPAM60 triblock copolymer in aqueous solution. The copolymer used a commercially available precursor modified with an atom transfer radical polymerization (ATRP) initiator to produce an ABA triblock copolymer via ATRP. Small-angle neutron scattering (SANS) was used to shed light on the structures of nanoparticles formed in aqueous solutions of this copolymer at two temperatures, 25 and 40 °C. The poly(dimethylsiloxane) block is very hydrophobic and poly(N-isopropylacrylamide) (PNIPAM) is thermoresponsive. SANS data at 25 °C indicates that the solutions of PNIPAM–b-PDMS–b-PNIPAM copolymers form well-defined aggregates with presumably core–shell structures below cloud point temperature. The scattering curves originating from nanoparticles formed at 40 °C in 100% D2O or 100% H2O were successfully fitted with the Beaucage model describing aggregates with hierarchical structure. | en |
dc.format.extent | 9 | |
dc.language.iso | eng | |
dc.relation.ispartof | Colloid and Polymer Science | |
dc.subject | thermoresponsive | |
dc.subject | PNIPAM | |
dc.subject | SANS | |
dc.subject | Polymerization | |
dc.subject | Atom transfer radical polymerization (ATRP) | |
dc.subject | self-assembly | |
dc.title | Synthesis and solution properties of a temperature-responsive PNIPAM–b-PDMS–b-PNIPAM triblock copolymer | en |
dc.contributor.institution | School of Life and Medical Sciences | |
dc.contributor.institution | Department of Pharmacy, Pharmacology and Postgraduate Medicine | |
dc.contributor.institution | Centre for Research into Topical Drug Delivery and Toxicology | |
dc.description.status | Peer reviewed | |
dc.date.embargoedUntil | 2018-04-05 | |
rioxxterms.version | AM | |
rioxxterms.versionofrecord | https://doi.org/10.1007/s00396-017-4084-y | |
rioxxterms.type | Journal Article/Review | |
herts.preservation.rarelyaccessed | true | |