University of Hertfordshire Research Archive

        JavaScript is disabled for your browser. Some features of this site may not work without it.

        Browse

        All of UHRABy Issue DateAuthorsTitlesThis CollectionBy Issue DateAuthorsTitles

        Arkivum Files

        My Downloads
        View Item 
        • UHRA Home
        • University of Hertfordshire
        • Research publications
        • View Item
        • UHRA Home
        • University of Hertfordshire
        • Research publications
        • View Item

        Vesiclepedia : a compendium for extracellular vesicles with continuous community annotation

        View/Open
        journal.pbio.1001450.pdf (PDF, 441Kb)
        Author
        Kalra, Hina
        Simpson, Richard J
        Ji, Hong
        Aikawa, Elena
        Altevogt, Peter
        Askenase, Philip
        Bond, Vincent C
        Borràs, Francesc E
        Breakefield, Xandra
        Budnik, Vivian
        Buzas, Edit
        Camussi, Giovanni
        Clayton, Aled
        Cocucci, Emanuele
        Falcon-Perez, Juan M
        Gabrielsson, Susanne
        Gho, Yong Song
        Gupta, Dwijendra
        Harsha, H C
        Hendrix, An
        Hill, Andrew F
        Inal, Jameel M
        Jenster, Guido
        Krämer-Albers, Eva-Maria
        Lim, Sai Kiang
        Llorente, Alicia
        Lötvall, Jan
        Marcilla, Antonio
        Mincheva-Nilsson, Lucia
        Nazarenko, Irina
        Nieuwland, Rienk
        Nolte-'t Hoen, Esther N M
        Pandey, Akhilesh
        Patel, Tushar
        Piper, Melissa G
        Pluchino, Stefano
        Prasad, T S Keshava
        Rajendran, Lawrence
        Raposo, Graca
        Record, Michel
        Reid, Gavin E
        Sánchez-Madrid, Francisco
        Schiffelers, Raymond M
        Siljander, Pia
        Stensballe, Allan
        Stoorvogel, Willem
        Taylor, Douglas
        Thery, Clotilde
        Valadi, Hadi
        van Balkom, Bas W M
        Vázquez, Jesús
        Vidal, Michel
        Wauben, Marca H M
        Yáñez-Mó, María
        Zoeller, Margot
        Mathivanan, Suresh
        Attention
        2299/20315
        Abstract
        Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into their microenvironment. Recent studies have elucidated the role of EVs in intercellular communication, pathogenesis, drug, vaccine and gene-vector delivery, and as possible reservoirs of biomarkers. These findings have generated immense interest, along with an exponential increase in molecular data pertaining to EVs. Here, we describe Vesiclepedia, a manually curated compendium of molecular data (lipid, RNA, and protein) identified in different classes of EVs from more than 300 independent studies published over the past several years. Even though databases are indispensable resources for the scientific community, recent studies have shown that more than 50% of the databases are not regularly updated. In addition, more than 20% of the database links are inactive. To prevent such database and link decay, we have initiated a continuous community annotation project with the active involvement of EV researchers. The EV research community can set a gold standard in data sharing with Vesiclepedia, which could evolve as a primary resource for the field.
        Publication date
        2012-12-18
        Published in
        Plos Biology
        Published version
        https://doi.org/10.1371/journal.pbio.1001450
        Other links
        http://hdl.handle.net/2299/20315
        Metadata
        Show full item record
        Keep in touch

        © 2019 University of Hertfordshire

        I want to...

        • Apply for a course
        • Download a Prospectus
        • Find a job at the University
        • Make a complaint
        • Contact the Press Office

        Go to...

        • Accommodation booking
        • Your student record
        • Bayfordbury
        • KASPAR
        • UH Arts

        The small print

        • Terms of use
        • Privacy and cookies
        • Criminal Finances Act 2017
        • Modern Slavery Act 2015
        • Sitemap

        Find/Contact us

        • T: +44 (0)1707 284000
        • E: ask@herts.ac.uk
        • Where to find us
        • Parking
        • hr
        • qaa
        • stonewall
        • AMBA
        • ECU Race Charter
        • disability confident
        • AthenaSwan