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dc.contributor.authorGurusamy, Kurinchi
dc.contributor.authorWalmsley, Martine
dc.contributor.authorDavidson, Brian R
dc.contributor.authorFrier, Claire
dc.contributor.authorFuller, Barry
dc.contributor.authorMadden, Angela
dc.contributor.authorMasson, Steve
dc.contributor.authorMorley, Richard
dc.contributor.authorSafarik, Ivana
dc.contributor.authorTsochatzis, Emmanouil
dc.contributor.authorAhmed, Irfan
dc.contributor.authorCowlin, Maxine
dc.contributor.authorDillon, John F
dc.contributor.authorEllicott, Graham
dc.contributor.authorElsharkawy, Ahmed M
dc.contributor.authorFarrington, Liz
dc.contributor.authorGlachan, Anthony
dc.contributor.authorKumar, Nagappan
dc.contributor.authorMilne, EJ
dc.contributor.authorRushbrook, Simon M
dc.contributor.authorSmith, Amanda
dc.contributor.authorStafford, LIzzie
dc.contributor.authorYeoman, Andrew
dc.date.accessioned2019-03-14T15:38:26Z
dc.date.available2019-03-14T15:38:26Z
dc.date.issued2019-03-07
dc.identifier.citationGurusamy , K , Walmsley , M , Davidson , B R , Frier , C , Fuller , B , Madden , A , Masson , S , Morley , R , Safarik , I , Tsochatzis , E , Ahmed , I , Cowlin , M , Dillon , J F , Ellicott , G , Elsharkawy , A M , Farrington , L , Glachan , A , Kumar , N , Milne , EJ , Rushbrook , S M , Smith , A , Stafford , LI & Yeoman , A 2019 , ' Top research priorities in liver and gallbladder disorders in the UK ' , BMJ Open , vol. 9 , no. 3 , e025045 , pp. 1-9 . https://doi.org/10.1136/bmjopen-2018-025045
dc.identifier.issn2044-6055
dc.identifier.otherPURE: 16224005
dc.identifier.otherPURE UUID: 2f63e04f-2050-4af5-9e25-68e5aa7a4de9
dc.identifier.otherScopus: 85062610216
dc.identifier.urihttp://hdl.handle.net/2299/21192
dc.description© Author(s) 2019. Published by BMJ.
dc.description.abstractOBJECTIVES: There is a mismatch between research questions considered important by patients, carers and healthcare professionals and the research performed in many fields of medicine. The non-alcohol-related liver and gallbladder disorders priority setting partnership was established to identify the top research priorities in the prevention, diagnostic and treatment of gallbladder disorders and liver disorders not covered by the James-Lind Alliance (JLA) alcohol-related liver disease priority setting partnership. DESIGN: The methods broadly followed the principles of the JLA guidebook. The one major deviation from the JLA methodology was the final step of identifying priorities: instead of prioritisation by group discussions at a consensus workshop involving stakeholders, the prioritisation was achieved by a modified Delphi consensus process. RESULTS: A total of 428 unique valid diagnostic or treatment research questions were identified. A literature review established that none of these questions were considered 'answered' that is, high-quality systematic reviews suggest that further research is not required on the topic. The Delphi panel achieved consensus (at least 80% Delphi panel members agreed) that a research question was a top research priority for six questions. Four additional research questions with highest proportion of Delphi panel members ranking the question as highly important were added to constitute the top 10 research priorities. CONCLUSIONS: A priority setting process involving patients, carers and healthcare professionals has been used to identify the top 10priority areas for research related to liver and gallbladder disorders. Basic, translational, clinical and public health research are required to address these uncertainties.en
dc.format.extent9
dc.language.isoeng
dc.relation.ispartofBMJ Open
dc.subjectchronic liver disease
dc.subjectliver
dc.subjectMedicine(all)
dc.titleTop research priorities in liver and gallbladder disorders in the UKen
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionDepartment of Biological and Environmental Sciences
dc.contributor.institutionAllied Health Professions
dc.contributor.institutionFood Policy, Nutrition and Diet
dc.contributor.institutionWeight and Obesity Research Group
dc.contributor.institutionBiosciences Research Group
dc.contributor.institutionAgriculture, Food and Veterinary Sciences
dc.description.statusPeer reviewed
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85062610216&partnerID=8YFLogxK
rioxxterms.versionVoR
rioxxterms.versionofrecordhttps://doi.org/10.1136/bmjopen-2018-025045
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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