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dc.contributor.authorYousif, Nada
dc.contributor.authorVaizey, Carolynne J
dc.contributor.authorMaeda, Yasuko
dc.date.accessioned2019-04-24T14:03:49Z
dc.date.available2019-04-24T14:03:49Z
dc.date.issued2019-03-11
dc.identifier.citationYousif , N , Vaizey , C J & Maeda , Y 2019 , ' Mapping the current flow in sacral nerve stimulation using computational modelling ' , Healthcare Technology Letters , vol. 6 , no. 1 , pp. 8-12 . https://doi.org/10.1049/htl.2018.5030
dc.identifier.issn2053-3713
dc.identifier.otherPURE: 15944878
dc.identifier.otherPURE UUID: aa55f202-32f7-4b26-b7fc-4eab9b373c60
dc.identifier.otherPubMed: 30881693
dc.identifier.otherPubMed: 30881693
dc.identifier.otherPubMedCentral: PMC6407445
dc.identifier.otherScopus: 85062707761
dc.identifier.urihttp://hdl.handle.net/2299/21296
dc.description© The Institution of Engineering and Technology 2019
dc.description.abstractSacral nerve stimulation (SNS) is an established treatment for faecal incontinence involving the implantation of a quadripolar electrode into a sacral foramen, through which an electrical stimulus is applied. Little is known about the induced spread of electric current around the SNS electrode and its effect on adjacent tissues, which limits optimisation of this treatment. The authors constructed a 3-dimensional imaging based finite element model in order to calculate and visualise the stimulation induced current and coupled this to biophysical models of nerve fibres. They investigated the impact of tissue inhomogeneity, electrode model choice and contact configuration and found a number of effects. (i) The presence of anatomical detail changes the estimate of stimulation effects in size and shape. (ii) The difference between the two models of electrodes is minimal for electrode contacts of the same length. (iii) Surprisingly, in this arrangement of electrode and neural fibre, monopolar and bipolar stimulation induce a similar effect. (iv) Interestingly when the active contact is larger, the volume of tissue activated reduces. This work establishes a protocol to better understand both therapeutic and adverse stimulation effects and in the future will enable patient-specific adjustments of stimulation parameters.en
dc.format.extent5
dc.language.isoeng
dc.relation.ispartofHealthcare Technology Letters
dc.rightsOpen
dc.subjectHealth Informatics
dc.subjectHealth Information Management
dc.titleMapping the current flow in sacral nerve stimulation using computational modellingen
dc.contributor.institutionCentre for Engineering Research
dc.contributor.institutionSchool of Engineering and Technology
dc.description.statusPeer reviewed
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85062707761&partnerID=8YFLogxK
dc.relation.schoolSchool of Engineering and Technology
dc.description.versiontypeFinal Published version
dcterms.dateAccepted2019-03-11
rioxxterms.versionVoR
rioxxterms.versionofrecordhttps://doi.org/10.1049/htl.2018.5030
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue
herts.rights.accesstypeOpen


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