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        Effects of Montmorency Tart Cherry Supplementation on Cardio-Metabolic Markers in Metabolic Syndrome Participants: a pilot study

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        Final Accepted Version (PDF, 839Kb)
        Author
        Desai, Terun
        Roberts, Michael
        Bottoms, Lindsay
        Attention
        2299/21432
        Abstract
        This study compared acute supplementation of Montmorency tart cherries in capsule (MTCC) and juice (MTCJ) forms in MetS humans, as potential prophylactic interventions against cardio-metabolic diseases. In an acute, single-blind, placebo-controlled, randomised, crossover trial, eleven participants with MetS (49 ± 12 years; 6M/5F), consumed one bolus of MTCC, MTCJ or placebo (PLA) on different occasions. Blood-based and functional cardio-metabolic biomarkers were measured pre-bolus and up to 5 h post-bolus. MTCJ significantly reduced systolic blood pressure compared to PLA at 2-h post-bolus (P = 0.018). Insulin was significantly lower with MTCC (P = 0.016) and MTCJ (P = 0.028) than PLA at 1-h and 3-h post-bolus, respectively. No significant differences between MTCC and MTCJ were seen. This study demonstrated for the first time that MTCC could reduce insulin concentrations in humans. Importantly, MTCJ induced a clinically relevant reduction in systolic blood pressure and also lowered insulin compared to PLA, in MetS humans.
        Publication date
        2019-04-16
        Published in
        Journal of Functional Foods
        Published version
        https://doi.org/10.1016/j.jff.2019.04.005
        License
        http://creativecommons.org/licenses/by-nc-nd/4.0/
        Other links
        http://hdl.handle.net/2299/21432
        Relations
        School of Life and Medical Sciences
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