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dc.contributor.authorChilcott, Robert
dc.contributor.authorLarner, Joanne
dc.contributor.authorDurrant, Adam
dc.contributor.authorHughes, Philip
dc.contributor.authorMahalingam, Devanya
dc.contributor.authorRivers, Samantha
dc.contributor.authorThomas, Elliot
dc.contributor.authorAmer, Nevine
dc.contributor.authorBarrett, Mark
dc.contributor.authorMatar, Hazem
dc.contributor.authorPinhal, Andreia
dc.contributor.authorJackson, Toni
dc.contributor.authorMcCarthy-Barnett, Kate
dc.contributor.authorReppucci, Joseph
dc.date.accessioned2019-07-29T11:08:57Z
dc.date.available2019-07-29T11:08:57Z
dc.date.issued2019-06-01
dc.identifier.citationChilcott , R , Larner , J , Durrant , A , Hughes , P , Mahalingam , D , Rivers , S , Thomas , E , Amer , N , Barrett , M , Matar , H , Pinhal , A , Jackson , T , McCarthy-Barnett , K & Reppucci , J 2019 , ' Evaluation of US Federal Guidelines (Primary Response Incident Scene Management [PRISM]) for Mass Decontamination of Casualties During the Initial Operational Response to a Chemical Incident ' , Annals of Emergency Medicine , vol. 73 , no. 6 , pp. 671-684 . https://doi.org/10.1016/j.annemergmed.2018.06.042
dc.identifier.issn0196-0644
dc.identifier.urihttp://hdl.handle.net/2299/21483
dc.description.abstractStudy objective The aim of this study was to evaluate the clinical and operational effectiveness of US federal government guidance (Primary Response Incident Scene Management [PRISM]) for the initial response phase to chemical incidents. Methods The study was performed as a large-scale exercise (Operation DOWNPOUR). Volunteers were dosed with a chemical warfare agent simulant to quantify the efficacy of different iterations of dry, ladder pipe system, or technical decontamination. Results The most effective process was a triple combination of dry, ladder pipe system, and technical decontamination, which attained an average decontamination efficiency of approximately 100% on exposed hair and skin sites. Both wet decontamination processes (ladder pipe system and technical decontamination, alone or in combination with dry decontamination) were also effective (decontamination efficiency >96%). In compliant individuals, dry decontamination was effective (decontamination efficiency approximately 99%), but noncompliance (tentatively attributed to suboptimal communication) resulted in significantly reduced efficacy (decontamination efficiency approximately 70%). At-risk volunteers (because of chronic illness, disability, or language barrier) were 3 to 8 times slower than ambulatory casualties in undergoing dry and ladder pipe system decontamination, a consequence of which may be a reduction in the overall rate at which casualties can be processed. Conclusion The PRISM incident response protocols are fit for purpose for ambulatory casualties. However, a more effective communication strategy is required for first responders (particularly when guiding dry decontamination). There is a clear need to develop more appropriate decontamination procedures for at-risk casualties.en
dc.format.extent14
dc.format.extent875508
dc.language.isoeng
dc.relation.ispartofAnnals of Emergency Medicine
dc.subjectEmergency Medicine
dc.titleEvaluation of US Federal Guidelines (Primary Response Incident Scene Management [PRISM]) for Mass Decontamination of Casualties During the Initial Operational Response to a Chemical Incidenten
dc.contributor.institutionDepartment of Pharmacy, Pharmacology and Postgraduate Medicine
dc.contributor.institutionCentre for Research into Topical Drug Delivery and Toxicology
dc.contributor.institutionPharmaceutics
dc.contributor.institutionToxicology
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionCentre for Applied Clinical, Health and Care Research (CACHE)
dc.contributor.institutionDepartment of Clinical, Pharmaceutical and Biological Science
dc.description.statusPeer reviewed
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85052502032&partnerID=8YFLogxK
rioxxterms.versionofrecord10.1016/j.annemergmed.2018.06.042
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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