Common and Distinct Functional Brain Networks for Intuitive and Deliberate Decision Making
Done, D. John
Reinforcement learning studies in rodents and primates demonstrate that goal-directed and habitual choice behaviors are mediated through different fronto-striatal systems, but the evidence is less clear in humans. In this study, functional magnetic resonance imaging (fMRI) data were collected whilst participants ( n = 20) performed a conditional associative learning task in which blocks of novel conditional stimuli (CS) required a deliberate choice, and blocks of familiar CS required an intuitive choice. Using standard subtraction analysis for fMRI event-related designs, activation shifted from the dorso-fronto-parietal network, which involves dorsolateral prefrontal cortex (DLPFC) for deliberate choice of novel CS, to ventro-medial frontal (VMPFC) and anterior cingulate cortex for intuitive choice of familiar CS. Supporting this finding, psycho-physiological interaction (PPI) analysis, using the peak active areas within the PFC for novel and familiar CS as seed regions, showed functional coupling between caudate and DLPFC when processing novel CS and VMPFC when processing familiar CS. These findings demonstrate separable systems for deliberate and intuitive processing, which is in keeping with rodent and primate reinforcement learning studies, although in humans they operate in a dynamic, possibly synergistic, manner particularly at the level of the striatum.
Published inBrain Sciences
MetadataShow full item record
Showing items related by title, author, creator and subject.
Assessing the quality of decision support technologies using the International Patient Decision Aid Standards instrument (IPDASi) Elwyn, Glyn; O'Connor, Annette M; Bennett, Carol; Newcombe, Robert G; Politi, Mary; Durand, Marie-Anne; Drake, Elizabeth; Joseph-Williams, Natalie; Khangura, Sara; Saarimaki, Anton; Sivell, Stephanie; Stiel, Mareike; Bernstein, Steven J; Col, Nananda; Coulter, Angela; Eden, Karen; Härter, Martin; Rovner, Margaret Holmes; Moumjid, Nora; Stacey, Dawn; Thomson, Richard; Whelan, Tim; van der Weijden, Trudy; Edwards, Adrian (2009)To describe the development, validation and inter-rater reliability of an instrument to measure the quality of patient decision support technologies (decision aids).
A Hybrid Hierarchical Decision Support System for Cardiac Surgical Intensive Care Patients. Part I : Physiological Modeling and Decision Support Design Denai, Mouloud; Mahfouf, M.; Ross, J.J. (2009-01)To develop a clinical decision support system (CDSS) that models the different levels of the clinician's decision-making strategies when controlling post cardiac surgery patients weaned from cardio pulmonary bypass
Ethical dimensions of management decision-making : a stakeholder values approach to performance and strategy Stainer, Lorice (University of Hertfordshire, 2003)The research shows how organisations can improve their strategic management decision-making, in the competitive global arena, through taking into account not only economic criteria but also ethical and environmental ...