dc.contributor.author | Ternik, Robert | |
dc.contributor.author | Liu, Fang | |
dc.contributor.author | Bartlett, Jeremy A | |
dc.contributor.author | Khong, Yuet Mei | |
dc.contributor.author | Thiam Tan, David Cheng | |
dc.contributor.author | Dixit, Trupti | |
dc.contributor.author | Wang, Siri | |
dc.contributor.author | Galella, Elizabeth A | |
dc.contributor.author | Gao, Zhihui | |
dc.contributor.author | Klein, Sandra | |
dc.date.accessioned | 2019-10-26T00:06:55Z | |
dc.date.available | 2019-10-26T00:06:55Z | |
dc.date.issued | 2018-02-05 | |
dc.identifier.citation | Ternik , R , Liu , F , Bartlett , J A , Khong , Y M , Thiam Tan , D C , Dixit , T , Wang , S , Galella , E A , Gao , Z & Klein , S 2018 , ' Assessment of swallowability and palatability of oral dosage forms in children : Report from an M-CERSI pediatric formulation workshop ' , International Journal of Pharmaceutics , vol. 536 , no. 2 , pp. 570-581 . https://doi.org/10.1016/j.ijpharm.2017.08.088 | |
dc.identifier.issn | 0378-5173 | |
dc.identifier.uri | http://hdl.handle.net/2299/21796 | |
dc.description | © 2017 Elsevier B.V. This manuscript is made available under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND 4.0). For further details please see: https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.description.abstract | The acceptability of pediatric pharmaceutical products to patients and their caregivers can have a profound impact on the resulting therapeutic outcome. However, existing methodology and approaches used for acceptability assessments for pediatric products is fragmented, making robust and consistent product evaluations difficult. A pediatric formulation development workshop took place in Washington, DC in June 2016 through the University of Maryland's Center of Excellence in Regulatory Science and Innovation (M-CERSI). A session at the workshop was dedicated to acceptability assessments and focused on two major elements that affect the overall acceptability of oral medicines, namely swallowability and palatability. The session started with presentations to provide an overview of literature, background and current state on swallowability and palatability assessments. Five parallel breakout discussions followed the presentations on each element, focusing on three overarching themes, risk-based approaches, methodology and product factors. This article reports the key outcomes of the workshop related to swallowability and palatability assessments. | en |
dc.format.extent | 12 | |
dc.format.extent | 1105758 | |
dc.language.iso | eng | |
dc.relation.ispartof | International Journal of Pharmaceutics | |
dc.subject | Journal Article | |
dc.title | Assessment of swallowability and palatability of oral dosage forms in children : Report from an M-CERSI pediatric formulation workshop | en |
dc.contributor.institution | Department of Pharmacy, Pharmacology and Postgraduate Medicine | |
dc.contributor.institution | School of Life and Medical Sciences | |
dc.contributor.institution | Bioadhesive Drug Delivery Group | |
dc.contributor.institution | Pharmaceutics | |
dc.contributor.institution | Pharmaceutical Analysis and Product Characterisation | |
dc.contributor.institution | Centre for Research into Topical Drug Delivery and Toxicology | |
dc.description.status | Peer reviewed | |
dc.date.embargoedUntil | 2019-02-13 | |
rioxxterms.versionofrecord | 10.1016/j.ijpharm.2017.08.088 | |
rioxxterms.type | Journal Article/Review | |
herts.preservation.rarelyaccessed | true | |