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dc.contributor.authorTernik, Robert
dc.contributor.authorLiu, Fang
dc.contributor.authorBartlett, Jeremy A
dc.contributor.authorKhong, Yuet Mei
dc.contributor.authorThiam Tan, David Cheng
dc.contributor.authorDixit, Trupti
dc.contributor.authorWang, Siri
dc.contributor.authorGalella, Elizabeth A
dc.contributor.authorGao, Zhihui
dc.contributor.authorKlein, Sandra
dc.date.accessioned2019-10-26T00:06:55Z
dc.date.available2019-10-26T00:06:55Z
dc.date.issued2018-02-05
dc.identifier.citationTernik , R , Liu , F , Bartlett , J A , Khong , Y M , Thiam Tan , D C , Dixit , T , Wang , S , Galella , E A , Gao , Z & Klein , S 2018 , ' Assessment of swallowability and palatability of oral dosage forms in children : Report from an M-CERSI pediatric formulation workshop ' , International Journal of Pharmaceutics , vol. 536 , no. 2 , pp. 570-581 . https://doi.org/10.1016/j.ijpharm.2017.08.088
dc.identifier.issn0378-5173
dc.identifier.otherPURE: 12685858
dc.identifier.otherPURE UUID: 2d854fd8-6961-4eef-b3cb-3a3ab93c1933
dc.identifier.otherPubMed: 28844897
dc.identifier.otherScopus: 85032205454
dc.identifier.urihttp://hdl.handle.net/2299/21796
dc.description© 2017 Elsevier B.V. This manuscript is made available under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND 4.0). For further details please see: https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.description.abstractThe acceptability of pediatric pharmaceutical products to patients and their caregivers can have a profound impact on the resulting therapeutic outcome. However, existing methodology and approaches used for acceptability assessments for pediatric products is fragmented, making robust and consistent product evaluations difficult. A pediatric formulation development workshop took place in Washington, DC in June 2016 through the University of Maryland's Center of Excellence in Regulatory Science and Innovation (M-CERSI). A session at the workshop was dedicated to acceptability assessments and focused on two major elements that affect the overall acceptability of oral medicines, namely swallowability and palatability. The session started with presentations to provide an overview of literature, background and current state on swallowability and palatability assessments. Five parallel breakout discussions followed the presentations on each element, focusing on three overarching themes, risk-based approaches, methodology and product factors. This article reports the key outcomes of the workshop related to swallowability and palatability assessments.en
dc.format.extent12
dc.language.isoeng
dc.relation.ispartofInternational Journal of Pharmaceutics
dc.subjectJournal Article
dc.titleAssessment of swallowability and palatability of oral dosage forms in children : Report from an M-CERSI pediatric formulation workshopen
dc.contributor.institutionDepartment of Pharmacy, Pharmacology and Postgraduate Medicine
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionBioadhesive Drug Delivery Group
dc.contributor.institutionPharmaceutics
dc.contributor.institutionPharmaceutical Analysis and Product Characterisation
dc.contributor.institutionCentre for Research into Topical Drug Delivery and Toxicology
dc.description.statusPeer reviewed
dc.date.embargoedUntil2019-02-13
rioxxterms.versionAM
rioxxterms.versionofrecordhttps://doi.org/10.1016/j.ijpharm.2017.08.088
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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