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dc.contributor.authorLuo, Qiwu
dc.contributor.authorSong, Cao
dc.contributor.authorYang, Chunhua
dc.contributor.authorGui, Weihua
dc.contributor.authorSun, Yichuang
dc.contributor.authorJeffrey, Zoe
dc.date.accessioned2020-01-07T01:07:23Z
dc.date.available2020-01-07T01:07:23Z
dc.date.issued2019-12-10
dc.identifier.citationLuo , Q , Song , C , Yang , C , Gui , W , Sun , Y & Jeffrey , Z 2019 , ' Headspace Oxygen Concentration Measurement for Pharmaceutical Glass Bottles in Open-path Optical Environment Using TDLAS/WMS ' , IEEE Transactions on Instrumentation and Measurement , vol. 69 , no. 8 , pp. 1-13 . https://doi.org/10.1109/TIM.2019.2958582
dc.identifier.issn0018-9456
dc.identifier.otherPURE: 17804147
dc.identifier.otherPURE UUID: 7bb526d2-54c2-4bc7-a347-0cb774344661
dc.identifier.otherScopus: 85091783854
dc.identifier.urihttp://hdl.handle.net/2299/22037
dc.description© 2019 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
dc.description.abstractAccurate measurement of oxygen concentration for pharmaceutical glass bottles is of great significance to ensure the asepsis of medicine and stability of ingredients. With merits of high sensitivity, low cost, non-contact, and real time response, the wavelength-modulation-based tunable diode laser absorption spectroscopy (TDLAS/WMS) technology shows great potential to achieve in-site oxygen concentration detection by the single-line spectrum measurement. This paper focuses on headspace oxygen concentration measurement in open-path optical environment, which is extremely challenging owing to the short light path length and random ambient noises. First, a signal reconstruction method is established based on discrete-time wavelet packet transform (DWPT), where random noise suppression is implicitly achieved. Then, oxygen concentration is inversed among the data between two adjacent valley values of the demodulated 2nd harmonic signal by multiple linear regression (MLR), and the linear discriminant analysis (LDA) is imported to enhance the information sparsity of 2nd harmonic signal matrix and to address the multi-collinearity problem. Simulation results prove our proposed method achieved considerable detection accuracy with average absolute error of 0.05%. This paper also designed a TDLAS/WMS prototype, the experimental results aiming at glass bottles with different oxygen concentration of 0%, 5%, 10% and 21% in open path optical environment indicate our method has achieved an encouraging average absolute error of 0.54%, and can survive well when the normalized SNR is within 0.85 to 1. These results promise that the proposed methodology can be widely applied in in-site AOI instrumentation of headspace oxygen concentration measurement for glass vials.en
dc.format.extent13
dc.language.isoeng
dc.relation.ispartofIEEE Transactions on Instrumentation and Measurement
dc.subjectAOI, TDLAS, WMS, oxygen concentration
dc.titleHeadspace Oxygen Concentration Measurement for Pharmaceutical Glass Bottles in Open-path Optical Environment Using TDLAS/WMSen
dc.contributor.institutionCentre for Engineering Research
dc.contributor.institutionCommunications and Intelligent Systems
dc.contributor.institutionSchool of Physics, Engineering & Computer Science
dc.contributor.institutionDepartment of Engineering and Technology
dc.description.statusPeer reviewed
rioxxterms.versionAM
rioxxterms.versionofrecordhttps://doi.org/10.1109/TIM.2019.2958582
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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