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Anosognosia for hemiplegia as a tripartite disconnection syndrome

dc.contributor.authorPacella, Valentina
dc.contributor.authorFoulon, Chris
dc.contributor.authorJenkinson, Paul M
dc.contributor.authorScandola, Michele
dc.contributor.authorBertagnoli, Sara
dc.contributor.authorAvesani, Renato
dc.contributor.authorFotopoulou, Aikaterini
dc.contributor.authorMoro, Valentina
dc.contributor.authorThiebaut de Schotten, Michel
dc.date.accessioned2020-02-15T01:14:12Z
dc.date.available2020-02-15T01:14:12Z
dc.date.issued2019-08-06
dc.identifier.citationPacella , V , Foulon , C , Jenkinson , P M , Scandola , M , Bertagnoli , S , Avesani , R , Fotopoulou , A , Moro , V & Thiebaut de Schotten , M 2019 , ' Anosognosia for hemiplegia as a tripartite disconnection syndrome ' , Elife , vol. 8 , e46075 . https://doi.org/10.7554/eLife.46075
dc.identifier.issn2050-084X
dc.identifier.otherORCID: /0000-0001-6887-0457/work/62749584
dc.identifier.urihttp://hdl.handle.net/2299/22224
dc.description© 2019 Pacella et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.
dc.description.abstractThe syndrome of Anosognosia for Hemiplegia (AHP) can provide unique insights into the neurocognitive processes of motor awareness. Yet, prior studies have only explored predominately discreet lesions. Using advanced structural neuroimaging methods in 174 patients with a right-hemisphere stroke, we were able to identify three neural systems that contribute to AHP, when disconnected or directly damaged: the (i) premotor loop (ii) limbic system, and (iii) ventral attentional network. Our results suggest that human motor awareness is contingent on the joint contribution of these three systems.en
dc.format.extent13
dc.format.extent5543064
dc.language.isoeng
dc.relation.ispartofElife
dc.subjectGeneral Neuroscience
dc.subjectGeneral Biochemistry,Genetics and Molecular Biology
dc.subjectGeneral Immunology and Microbiology
dc.titleAnosognosia for hemiplegia as a tripartite disconnection syndromeen
dc.contributor.institutionCentre for Research in Psychology and Sport Sciences
dc.contributor.institutionDepartment of Psychology and Sports Sciences
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionPsychology
dc.description.statusPeer reviewed
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85071177667&partnerID=8YFLogxK
rioxxterms.versionofrecord10.7554/eLife.46075
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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