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dc.contributor.authorGutierrez Gonzalez, Javier
dc.contributor.authorGarcia-Cela, Esther
dc.contributor.authorMagan, Naresh
dc.contributor.authorRahatekar, Sameer
dc.date.accessioned2020-04-22T00:07:18Z
dc.date.available2020-04-22T00:07:18Z
dc.date.issued2020-07-01
dc.identifier.citationGutierrez Gonzalez , J , Garcia-Cela , E , Magan , N & Rahatekar , S 2020 , ' Electrospinning Alginate/Polyethylene Oxide and Curcumin Composite Nanofibers ' , Materials Letters , vol. 270 , 127662 . https://doi.org/10.1016/j.matlet.2020.127662
dc.identifier.issn0167-577X
dc.identifier.otherPURE: 20400117
dc.identifier.otherPURE UUID: 10e626aa-f894-4b33-8fb5-c1323fb38e1b
dc.identifier.otherScopus: 85082684284
dc.identifier.urihttp://hdl.handle.net/2299/22625
dc.description© 2020 Elsevier Ltd. All rights reserved. This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence http://creativecommons.org/licenses/by-nc-nd/4.0/.
dc.description.abstractManufacturing a sodium alginate (SA) and polyethylene oxide (PEO) composite loaded with curcumin (CU) was accomplished in this study by using electrospinning. These composite nanofibers were crosslinked using trifluoroacetic acid (TFA) mechanically characterized along with the morphological properties of the composite nanofiber mesh. We were successful in manufacturing the composite nanofibers with a wide range of CU concentrations ranging from 10 to 40 wt%. Firstly, dissolved in a saturated water/CU solution it was added to SA/PEO blending, homogenized and electrospun. Mechanical properties were affected by both CU addition and the cross-linking process, resulting in a higher ultimate tensile stress (MPa) (from 4.3±2 to 15.1±2 at 10% CU) and Young modulus (GPa) (0.0076±0.003, 0.044±0.003 before and after TFA). CU was successfully encapsulated in the SA nanofibers and excellent mechanical properties were obtained. By using a biocompatible TFA crosslinking and the natural properties of alginate this nanofiber composite could potentially be used for filtering, environmental pollution control, food packaging and for tissue engineering.en
dc.format.extent4
dc.language.isoeng
dc.relation.ispartofMaterials Letters
dc.subjectBiomedical
dc.subjectCurcumin
dc.subjectElectrospinning
dc.subjectNanofibers
dc.subjectSodium alginate
dc.subjectMaterials Science(all)
dc.subjectCondensed Matter Physics
dc.subjectMechanics of Materials
dc.subjectMechanical Engineering
dc.titleElectrospinning Alginate/Polyethylene Oxide and Curcumin Composite Nanofibersen
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionDepartment of Biological and Environmental Sciences
dc.contributor.institutionAgriculture, Food and Veterinary Sciences
dc.contributor.institutionCrop Protection and Climate Change
dc.contributor.institutionCentre for Agriculture, Food and Environmental Management Research
dc.contributor.institutionBiosciences Research Group
dc.contributor.institutionDepartment of Clinical, Pharmaceutical and Biological Science
dc.description.statusPeer reviewed
dc.date.embargoedUntil2021-03-16
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85082684284&partnerID=8YFLogxK
rioxxterms.versionAM
rioxxterms.versionofrecordhttps://doi.org/10.1016/j.matlet.2020.127662
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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