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dc.contributor.authorVerheecke-Vaessen, C.
dc.contributor.authorMonte, J.
dc.contributor.authorGarcia-Cela, E.
dc.contributor.authorMagan, N.
dc.contributor.authorMedina, A.
dc.date.accessioned2020-07-18T00:07:52Z
dc.date.available2020-07-18T00:07:52Z
dc.date.issued2020-06-29
dc.identifier.citationVerheecke-Vaessen , C , Monte , J , Garcia-Cela , E , Magan , N & Medina , A 2020 , ' Proof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin production ' , Letters in Applied Microbiology . https://doi.org/10.1111/lam.13338
dc.identifier.issn0266-8254
dc.identifier.urihttp://hdl.handle.net/2299/22969
dc.description© 2020 The Authors. This is an open access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
dc.description.abstractThe objective was to screen 10 snake venoms for their efficacy to control growth and mycotoxin production by important mycotoxigenic fungi including Aspergillus flavus, Aspergillus westerdijkiae, Penicillium verrucosum, Fusarium graminearum and F. langsethiae. The Bioscreen C rapid assay system was used. The venoms from the Viperidae snake family delayed growth of some of the test fungi, especially F. graminearum and F. langsethiae and sometimes A. flavus. Some were also able to reduce mycotoxin production. The two most potent crude snake venoms (Naja nigricollis and N. siamensis; 41 and 43 fractions, respectively) were further fractionated and 83/84 of these fractions were able to reduce mycotoxin production by >90% in two of the mycotoxigenic fungi examined. This study suggests that there may be significant potential for the identification of novel fungistatic/fungicidal bioactive compounds as preservatives of raw and processed food commodities post-harvest from such snake venoms.en
dc.format.extent911657
dc.language.isoeng
dc.relation.ispartofLetters in Applied Microbiology
dc.subjectApplied Microbiology and Biotechnology
dc.titleProof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin productionen
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionDepartment of Pharmacy, Pharmacology and Postgraduate Medicine
dc.contributor.institutionDepartment of Clinical, Pharmaceutical and Biological Science
dc.description.statusPeer reviewed
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85087153431&partnerID=8YFLogxK
rioxxterms.versionofrecord10.1111/lam.13338
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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