dc.contributor.author | Desai, Terun | |
dc.contributor.author | Roberts, Michael | |
dc.contributor.author | Bottoms, Lindsay | |
dc.date.accessioned | 2020-08-18T00:05:51Z | |
dc.date.available | 2020-08-18T00:05:51Z | |
dc.date.issued | 2020-08-12 | |
dc.identifier.citation | Desai , T , Roberts , M & Bottoms , L 2020 , ' Effects of Short-Term Continuous Montmorency Tart Cherry Juice Supplementation in Participants with Metabolic Syndrome ' , European Journal of Nutrition , pp. 1 . https://doi.org/10.1007/s00394-020-02355-5 | |
dc.identifier.issn | 1436-6207 | |
dc.identifier.other | ORCID: /0000-0001-8606-0458/work/79184572 | |
dc.identifier.other | ORCID: /0000-0003-4632-3764/work/92337157 | |
dc.identifier.uri | http://hdl.handle.net/2299/23055 | |
dc.description | © 2020 Springer-Verlag. The final publication is available at Springer via https://doi.org/10.1007/s00394-020-02355-5 | |
dc.description.abstract | Purpose: Metabolic Syndrome (MetS) augments the incidence of cardiovascular disease by two-fold and type II diabetes mellitus by five-fold. Montmorency tart cherries are rich in phytochemicals shown to improve biomarkers related to cardio-metabolic health in humans. This study aimed to examine cardio-metabolic responses after 7-days Montmorency tart cherry juice (MTCJ) supplementation and also acute on short-term supplementation responses to a single bolus, in humans with MetS. Methods: In a randomised, single-blind, placebo-controlled, crossover trial, 12 participants with MetS (50 ± 10 years; 6M/6F), consumed MTCJ or placebo (PLA) for 7 days. Blood-based and functional cardio-metabolic biomarkers were measured pre- and post-supplementation, and acute responses measured pre-bolus and up to 5 h post-bolus on the 7th day. Results: 24-h ambulatory systolic (P = 0.016), diastolic (P = 0.009) blood pressure and mean arterial pressure (P = 0.041) were significantly lower after 7-days MTCJ supplementation compared to PLA. Glucose (P = 0.038), total cholesterol (P = 0.036), LDL (P = 0.023) concentrations, total cholesterol:HDL ratio (P = 0.004) and respiratory exchange ratio values (P = 0.009) were significantly lower after 6-days MTCJ consumption compared to PLA. Conclusions: This study revealed for the first time in humans that MTCJ significantly improved 24-h BP, fasting glucose, total cholesterol and total cholesterol:HDL ratio, and also lowered resting respiratory exchange ratio compared to a control group. Responses demonstrated clinically relevant improvements on aspects of cardio-metabolic function, emphasising the potential efficacy of MTCJ in preventing further cardio-metabolic dysregulation in participants with MetS. Registered at clinicaltrials.gov (NCT03619941). | en |
dc.format.extent | 17 | |
dc.format.extent | 1709137 | |
dc.language.iso | eng | |
dc.relation.ispartof | European Journal of Nutrition | |
dc.subject | Ambulatory blood pressure | |
dc.subject | Anthocyanins | |
dc.subject | Cardio-metabolic health | |
dc.subject | Diabetes | |
dc.subject | Functional foods | |
dc.subject | Hypertension | |
dc.subject | Medicine (miscellaneous) | |
dc.subject | Nutrition and Dietetics | |
dc.title | Effects of Short-Term Continuous Montmorency Tart Cherry Juice Supplementation in Participants with Metabolic Syndrome | en |
dc.contributor.institution | Centre for Research in Psychology and Sport Sciences | |
dc.contributor.institution | School of Life and Medical Sciences | |
dc.contributor.institution | Department of Psychology, Sport and Geography | |
dc.contributor.institution | Centre for Applied Clinical, Health and Care Research (CACHE) | |
dc.contributor.institution | Centre for Future Societies Research | |
dc.contributor.institution | High Performance Sport Research Group | |
dc.contributor.institution | Exercise, Health and Wellbeing Research Group | |
dc.description.status | Peer reviewed | |
dc.date.embargoedUntil | 2021-08-12 | |
dc.identifier.url | http://www.scopus.com/inward/record.url?scp=85089357683&partnerID=8YFLogxK | |
rioxxterms.versionofrecord | 10.1007/s00394-020-02355-5 | |
rioxxterms.type | Journal Article/Review | |
herts.preservation.rarelyaccessed | true | |