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dc.contributor.authorMartinotti, Giovanni
dc.contributor.authorGiorgetti, Raffaele
dc.contributor.authorSchifano, Fabrizio
dc.contributor.authordi Giannantonio, Massimo
dc.date.accessioned2020-09-08T00:06:48Z
dc.date.available2020-09-08T00:06:48Z
dc.date.issued2020-08-31
dc.identifier.citationMartinotti , G , Giorgetti , R , Schifano , F & di Giannantonio , M 2020 , ' Club Drugs: Psychotropic Effects and Psychopathological Characteristics of a Sample of Inpatients ' , Frontiers in Psychiatry , vol. 11 , 879 . https://doi.org/10.3389/fpsyt.2020.00879
dc.identifier.issn1664-0640
dc.identifier.otherPURE: 22473177
dc.identifier.otherPURE UUID: 8dcafdd3-cce5-4775-a91c-ee5aadc4d53f
dc.identifier.urihttp://hdl.handle.net/2299/23100
dc.description© 2020 Martinotti, Negri, Schiavone, Montemitro, Vannini, Baroni, Pettorruso, De Giorgio, Giorgetti, Verrastro, Trabace, Garcia, Castro, Iglesias Lopez, Merino Del Villar, Schifano and di Giannantonio. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY - https://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
dc.description.abstractBackground: growing evidence supports the possibility of significant psychiatric consequences related to novel and traditional psychoactive substance consumption. The problem of differential diagnosis has hampered research on specific psychopathologies with unclear outcomes. The aim of our study was to report psychiatric and clinical features of subjects admitted to a psychiatric ward in Ibiza, Spain, with a clinical diagnosis of substance abuse or intoxication. Methods: A survey was administered to a sample of inpatients hospitalized due to psychiatric symptoms related to recent use of psychoactive substances. The questionnaire investigated sociodemographic factors, familiar and personal anamnesis, substance use habits, general features and psychopathological features. Urine samples were collected and analysed in a toxicology laboratory using gas chromatography and mass spectrometry. Results: A total of 110 patients were included in the study. Most patients (70%) declared multiple substance use, and 33% of patients reported more than two substances; nevertheless, it was possible to identify 17 (15%) depressor users, 44 (40%) stimulant users and 49 (45%) psychodysleptics users. A positive association with a lifetime diagnosis of bipolar disorder was found (two-tailed Fisher’s exact test: p=0.013). Psychomotor agitation, reference and paranoid delusions, affective symptoms, consciousness disorders and aggressiveness represented some of the most frequent symptoms at entry evaluation. Conclusions: In this study, we described the acute psychiatric presentations related to recreational drug use in subjects on holiday in Ibiza. The use of psychoactive substances was characterised by poly-use of both traditional and novel substances, with several psychopathological consequences. Future research should focus on a better understanding of the psychopathological effects of specific substances, defining signs and symptoms to help make a differential diagnosis and prospectively examine long-term effects.en
dc.format.extent12
dc.language.isoeng
dc.relation.ispartofFrontiers in Psychiatry
dc.subjectClub drugs
dc.subjectNovel Psychoactive Substances
dc.subjectPsychopathology
dc.subjectPsychosis
dc.titleClub Drugs: Psychotropic Effects and Psychopathological Characteristics of a Sample of Inpatientsen
dc.contributor.institutionDepartment of Clinical and Pharmaceutical Sciences
dc.contributor.institutionCentre for Health Services and Clinical Research
dc.contributor.institutionPsychopharmacology, Drug Misuse and Novel Psychoactive Substances Unit
dc.contributor.institutionSchool of Life and Medical Sciences
dc.description.statusPeer reviewed
rioxxterms.versionVoR
rioxxterms.versionofrecordhttps://doi.org/10.3389/fpsyt.2020.00879
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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