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dc.contributor.authorZangani, Caroline
dc.contributor.authorSchifano, Fabrizio
dc.contributor.authorNapoletano, Flavia
dc.contributor.authorArillotta, Davide
dc.contributor.authorGilgar, Liam
dc.contributor.authorGuirguis, Amira
dc.contributor.authorCorkery, John Martin
dc.contributor.authorGambini, Orsola
dc.contributor.authorVento, Alessandro
dc.date.accessioned2020-10-14T00:09:34Z
dc.date.available2020-10-14T00:09:34Z
dc.date.issued2020-03-02
dc.identifier.citationZangani , C , Schifano , F , Napoletano , F , Arillotta , D , Gilgar , L , Guirguis , A , Corkery , J M , Gambini , O & Vento , A 2020 , ' The e-psychonauts’ ‘Spiced’ World; assessment of the synthetic cannabinoids’ information available online ' , Current Neuropharmacology , vol. 18 , no. 10 , pp. 966-1051 . https://doi.org/10.2174/1570159X18666200302125146
dc.identifier.issn1570-159X
dc.identifier.urihttp://hdl.handle.net/2299/23260
dc.description© 2020 Bentham Science. This is the accepted manuscript version of an article which has been published in final form at https://dx.doi.org/10.2174/1570159X18666200302125146.
dc.description.abstractBackground: A wide range of novel psychoactive substances (NPS) is regularly searched and discussed online by web-based drug enthusiasts (i.e. the e-psychonauts). Among NPS, the range of synthetic cannabinoids (SC; ‘Spice’) currently represents a challenge for governments and clinicians. Methods: Using a web crawler (i.e. the NPS.Finder®), the present study aimed at assessing psychonauts’ fora/platforms to better understand the online mentions of SC. Results: The open-web crawling/navigating software identified here some 1,103 synthetic cannabinoids. Of these, 863 molecules were not listed in either the international or the European NPS databases. Conclusion: A web crawling approach helped here in identifying a large range of unknown SC likely to possess a misuse potential. Most of these novel/emerging molecules are still relatively unknown. This is a reason for concern; each of these analogues potentially presents different toxicodynamic profiles and there is a lack of docking, preclinical, and clinical observations. Strengthening multidisciplinary collaboration between clinicians and bioinformatics may prove useful in better assessing SC-associated public health risks.en
dc.format.extent86
dc.format.extent2015964
dc.language.isoeng
dc.relation.ispartofCurrent Neuropharmacology
dc.subjectpsychonauts
dc.subjectNPS
dc.subjectnew psychoactive substances
dc.subjectsynthetic cannabinoids
dc.subjectweb crawling
dc.subjectWeb crawling
dc.subjectSynthetic cannabinoids
dc.subjectNew psychoactive substances
dc.subjectPsychonauts
dc.subjectClinical Neurology
dc.subjectNeurology
dc.subjectPsychiatry and Mental health
dc.subjectPharmacology (medical)
dc.subjectPharmacology
dc.titleThe e-psychonauts’ ‘Spiced’ World; assessment of the synthetic cannabinoids’ information available onlineen
dc.contributor.institutionDepartment of Clinical and Pharmaceutical Sciences
dc.contributor.institutionCentre for Health Services and Clinical Research
dc.contributor.institutionPsychopharmacology, Drug Misuse and Novel Psychoactive Substances Unit
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionCentre for Clinical Practice, Safe Medicines and Drug Misuse Research
dc.contributor.institutionDepartment of Clinical, Pharmaceutical and Biological Science
dc.description.statusPeer reviewed
dc.date.embargoedUntil2021-03-02
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85090874908&partnerID=8YFLogxK
rioxxterms.versionofrecord10.2174/1570159X18666200302125146
rioxxterms.typeOther
herts.preservation.rarelyaccessedtrue


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