dc.contributor.author | Patel, Hershna | |
dc.contributor.author | Kukol, Andreas | |
dc.date.accessioned | 2020-11-25T19:45:59Z | |
dc.date.available | 2020-11-25T19:45:59Z | |
dc.date.issued | 2020-11-19 | |
dc.identifier.citation | Patel , H & Kukol , A 2020 , ' Integrating molecular modelling methods to advance influenza A virus drug discovery ' , Drug Discovery Today . https://doi.org/10.1016/j.drudis.2020.11.014 | |
dc.identifier.issn | 1359-6446 | |
dc.identifier.uri | http://hdl.handle.net/2299/23518 | |
dc.description.abstract | Since the discovery of the anti-influenza drugs Oseltamivir and Zanamivir using computer aided drug design methods, there have been significant applications of molecular modelling methodologies applied to influenza A virus drug discovery, such as molecular dynamics simulation, molecular docking and virtual screening. This review provides a brief general introduction to molecular modelling in the context of drug discovery and then focuses on the advances and impact of integrating these methods with specific reference to potential influenza A antiviral drug targets. | en |
dc.format.extent | 2219555 | |
dc.language.iso | eng | |
dc.relation.ispartof | Drug Discovery Today | |
dc.title | Integrating molecular modelling methods to advance influenza A virus drug discovery | en |
dc.contributor.institution | Biosciences Research Group | |
dc.contributor.institution | School of Life and Medical Sciences | |
dc.contributor.institution | Department of Clinical, Pharmaceutical and Biological Science | |
dc.contributor.institution | Centre for Research in Mechanisms of Disease and Drug Discovery | |
dc.contributor.institution | Centre for Future Societies Research | |
dc.description.status | Peer reviewed | |
dc.date.embargoedUntil | 2021-11-19 | |
rioxxterms.versionofrecord | 10.1016/j.drudis.2020.11.014 | |
rioxxterms.type | Journal Article/Review | |
herts.preservation.rarelyaccessed | true | |