dc.contributor.author | Coe, Shelly | |
dc.contributor.author | Tektonidis, Thanasis G. | |
dc.contributor.author | Coverdale, Clare | |
dc.contributor.author | Penny, Sarah | |
dc.contributor.author | Collett, Johnny | |
dc.contributor.author | Chu, Bernard T.Y. | |
dc.contributor.author | Izadi, Hooshang | |
dc.contributor.author | Middleton, Rod | |
dc.contributor.author | Dawes, Helen | |
dc.date.accessioned | 2021-02-09T00:08:24Z | |
dc.date.available | 2021-02-09T00:08:24Z | |
dc.date.issued | 2021-01 | |
dc.identifier.citation | Coe , S , Tektonidis , T G , Coverdale , C , Penny , S , Collett , J , Chu , B T Y , Izadi , H , Middleton , R & Dawes , H 2021 , ' A cross sectional assessment of nutrient intake and the association of the inflammatory properties of nutrients and foods with symptom severity in a large cohort from the UK Multiple Sclerosis Registry ' , Nutrition Research , vol. 85 , pp. 31-39 . https://doi.org/10.1016/j.nutres.2020.11.006 | |
dc.identifier.issn | 0271-5317 | |
dc.identifier.other | ORCID: /0000-0002-9655-1389/work/88680241 | |
dc.identifier.uri | http://hdl.handle.net/2299/23874 | |
dc.description | Funding Information: Funding for this research was obtained from Oxford Brookes University. Professor Helen Dawes is supported by the Elizabeth Casson Trust and the NIHR Oxford Health Biomedical Research Centre. Publisher Copyright: © 2020 Copyright: Copyright 2021 Elsevier B.V., All rights reserved. | |
dc.description.abstract | To assess the intake of nutrients in people with multiple sclerosis (pwMS) compared to a control population, and to assess the pro/ anti-inflammatory properties of nutrients/ foods and their relationships with fatigue and quality of life. This was a cross sectional study in which 2410 pwMS (686 men; 1721 women, 3 n/a, mean age 53 (11 years)) provided dietary data using a food frequency questionnaire that was hosted on the MS Register for a period of 3 months and this was compared to a cohort of 24,852 controls (11,250 male, 13,602 female, mean age 59 years). Consent was implied by anonymously filling out the questionnaire. A Wilcoxon test was used to compare intake between pwMS and controls, and a bivariate analyses followed by chi2 test were undertaken to identify significance and the strength of the relationship between pro/anti-inflammatory dietary factors and fatigue and EQ-5D. Compared to controls, all nutrients were significantly lower in the MS group (P < .05). Bivariate associations showed a significant correlation between consuming fish and lower clinical fatigue (χ2(1) = 4.221, P< .05), with a very low association (φ (phi) = −0.051, P = .04. Positive health outcomes on the EQ-5D measures were associated with higher carotene, magnesium oily fish and fruits and vegetable and sodium consumption (P < .05). Fiber, red meat, and saturated fat (women only) consumption was associated with worse outcomes on the EQ-5D measures (P < .05). pwMS have different dietary intakes compared to controls, and this may be associated with worse symptoms. | en |
dc.format.extent | 9 | |
dc.format.extent | 1732646 | |
dc.language.iso | eng | |
dc.relation.ispartof | Nutrition Research | |
dc.subject | Diet | |
dc.subject | Fatigue | |
dc.subject | Inflammation | |
dc.subject | Multiple sclerosis | |
dc.subject | Quality of life | |
dc.subject | Endocrinology, Diabetes and Metabolism | |
dc.subject | Endocrinology | |
dc.subject | Nutrition and Dietetics | |
dc.title | A cross sectional assessment of nutrient intake and the association of the inflammatory properties of nutrients and foods with symptom severity in a large cohort from the UK Multiple Sclerosis Registry | en |
dc.contributor.institution | School of Life and Medical Sciences | |
dc.contributor.institution | Food Policy, Nutrition and Diet | |
dc.contributor.institution | Department of Clinical, Pharmaceutical and Biological Science | |
dc.contributor.institution | Centre for Agriculture, Food and Environmental Management Research | |
dc.contributor.institution | Agriculture, Food and Veterinary Sciences | |
dc.description.status | Peer reviewed | |
dc.date.embargoedUntil | 2021-11-20 | |
dc.identifier.url | http://www.scopus.com/inward/record.url?scp=85099235482&partnerID=8YFLogxK | |
rioxxterms.versionofrecord | 10.1016/j.nutres.2020.11.006 | |
rioxxterms.type | Journal Article/Review | |
herts.preservation.rarelyaccessed | true | |