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dc.contributor.authorBernstein, D E
dc.contributor.authorPiedad, J
dc.contributor.authorWest, A
dc.contributor.authorJohnston, Ian
dc.contributor.authorDimov, Nikolay
dc.contributor.authorInal, Jameel
dc.contributor.authorVasdev, Nikhil
dc.contributor.authorHemsworth, L
dc.date.accessioned2021-05-07T23:09:42Z
dc.date.available2021-05-07T23:09:42Z
dc.date.issued2021-04-29
dc.identifier.citationBernstein , D E , Piedad , J , West , A , Johnston , I , Dimov , N , Inal , J , Vasdev , N & Hemsworth , L 2021 , ' Prostate cancer and microfluids – Current status and Future applications ' , Urologic Oncology . https://doi.org/10.1016/j.urolonc.2021.03.010
dc.identifier.issn1078-1439
dc.identifier.otherPURE: 24846938
dc.identifier.otherPURE UUID: 95a48e3e-2141-48c5-b67f-9171676352bb
dc.identifier.otherORCID: /0000-0001-9696-3191/work/93470772
dc.identifier.otherORCID: /0000-0002-2873-1505/work/93471196
dc.identifier.otherScopus: 85104932839
dc.identifier.urihttp://hdl.handle.net/2299/24454
dc.description© 2021 Published by Elsevier Inc. This is the accepted manuscript version of an article which has been published in final form at https://doi.org/10.1016/j.urolonc.2021.03.010
dc.description.abstractIntroduction Microfluidic systems aim to detect sample matter quickly with high sensitivity and resolution, on a small scale. With its increased use in medicine, the field is showing significant promise in prostate cancer diagnosis and management due, in part, to its ability to offer point-of-care testing. This review highlights some of the research that has been undertaken in respect of prostate cancer and microfluidics. Methods Firstly, this review considers the diagnosis of prostate cancer through use of microfluidic systems and analyses the detection of prostate specific antigen, proteins, and circulating tumour cells to highlight the scope of current advancements. Secondly, this review analyses progressions in the understanding of prostate cancer physiology and considers techniques used to aid treatment of prostate cancer, such as the creation of a micro-environment. Finally, this review highlights potential future roles of microfluidics in assisting prostate cancer, such as in exosomal analysis. Conclusion In conclusion, this review shows the vast scope and application of microfluidic systems and how these systems will ensure advancements to future prostate cancer management.en
dc.format.extent16
dc.language.isoeng
dc.relation.ispartofUrologic Oncology
dc.rightsEmbargoed
dc.titleProstate cancer and microfluids – Current status and Future applicationsen
dc.contributor.institutionCentre for Climate Change Research
dc.contributor.institutionDepartment of Engineering and Technology
dc.contributor.institutionSchool of Physics, Engineering & Computer Science
dc.contributor.institutionExtracellular Vesicle Research Unit
dc.contributor.institutionBioEngineering
dc.contributor.institutionCentre for Research in Biodetection Technologies
dc.contributor.institutionMicro Electro-Mechanical Systems
dc.contributor.institutionCentre for Hazard Detection and Protection Research
dc.contributor.institutionMicrofluidics and Microengineering
dc.contributor.institutionCentre for Engineering Research
dc.contributor.institutionCentre for Health Services and Clinical Research
dc.contributor.institutionBasic and Clinical Science Unit
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionDepartment of Clinical, Pharmaceutical and Biological Science
dc.contributor.institutionBiosciences Research Group
dc.description.statusPeer reviewed
dc.date.embargoedUntil2021-04-29
dc.relation.schoolSchool of Physics, Engineering & Computer Science
dc.relation.schoolSchool of Life and Medical Sciences
dc.description.versiontypeFinal Accepted Version
dcterms.dateAccepted2021-04-29
rioxxterms.versionAM
rioxxterms.versionofrecordhttps://doi.org/10.1016/j.urolonc.2021.03.010
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue
herts.rights.accesstypeEmbargoed


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