dc.contributor.author | Bernstein, D E | |
dc.contributor.author | Piedad, J | |
dc.contributor.author | West, A | |
dc.contributor.author | Johnston, Ian | |
dc.contributor.author | Dimov, Nikolay | |
dc.contributor.author | Inal, Jameel | |
dc.contributor.author | Vasdev, Nikhil | |
dc.contributor.author | Hemsworth, L | |
dc.date.accessioned | 2021-05-07T23:09:42Z | |
dc.date.available | 2021-05-07T23:09:42Z | |
dc.date.issued | 2021-08-30 | |
dc.identifier.citation | Bernstein , D E , Piedad , J , West , A , Johnston , I , Dimov , N , Inal , J , Vasdev , N & Hemsworth , L 2021 , ' Prostate cancer and microfluids ' , Urologic Oncology: Seminars and Original Investigations , vol. 39 , no. 8 , pp. 455-470 . https://doi.org/10.1016/j.urolonc.2021.03.010 | |
dc.identifier.issn | 1078-1439 | |
dc.identifier.other | ORCID: /0000-0001-9696-3191/work/93470772 | |
dc.identifier.other | ORCID: /0000-0002-2873-1505/work/93471196 | |
dc.identifier.uri | http://hdl.handle.net/2299/24454 | |
dc.description | © 2021 Published by Elsevier Inc. This is the accepted manuscript version of an article which has been published in final form at https://doi.org/10.1016/j.urolonc.2021.03.010 | |
dc.description.abstract | Microfluidic systems aim to detect sample matter quickly with high sensitivity and resolution, on a small scale. With its increased use in medicine, the field is showing significant promise in prostate cancer diagnosis and management due, in part, to its ability to offer point-of-care testing. This review highlights some of the research that has been undertaken in respect of prostate cancer and microfluidics. Firstly, this review considers the diagnosis of prostate cancer through use of microfluidic systems and analyses the detection of prostate specific antigen, proteins, and circulating tumor cells to highlight the scope of current advancements. Secondly, this review analyses progressions in the understanding of prostate cancer physiology and considers techniques used to aid treatment of prostate cancer, such as the creation of a micro-environment. Finally, this review highlights potential future roles of microfluidics in assisting prostate cancer, such as in exosomal analysis. In conclusion, this review shows the vast scope and application of microfluidic systems and how these systems will ensure advancements to future prostate cancer management. | en |
dc.format.extent | 16 | |
dc.format.extent | 724926 | |
dc.language.iso | eng | |
dc.relation.ispartof | Urologic Oncology: Seminars and Original Investigations | |
dc.title | Prostate cancer and microfluids | en |
dc.contributor.institution | Centre for Climate Change Research (C3R) | |
dc.contributor.institution | Department of Engineering and Technology | |
dc.contributor.institution | School of Physics, Engineering & Computer Science | |
dc.contributor.institution | Extracellular Vesicle Research Unit | |
dc.contributor.institution | BioEngineering | |
dc.contributor.institution | Centre for Research in Biodetection Technologies | |
dc.contributor.institution | Micro Electro-Mechanical Systems | |
dc.contributor.institution | Centre for Hazard Detection and Protection Research | |
dc.contributor.institution | Microfluidics and Microengineering | |
dc.contributor.institution | Centre for Engineering Research | |
dc.contributor.institution | Centre for Health Services and Clinical Research | |
dc.contributor.institution | Basic and Clinical Science Unit | |
dc.contributor.institution | School of Life and Medical Sciences | |
dc.contributor.institution | Department of Clinical, Pharmaceutical and Biological Science | |
dc.contributor.institution | Biosciences Research Group | |
dc.description.status | Peer reviewed | |
dc.date.embargoedUntil | 2021-04-29 | |
dc.identifier.url | http://www.scopus.com/inward/record.url?scp=85104932839&partnerID=8YFLogxK | |
rioxxterms.versionofrecord | 10.1016/j.urolonc.2021.03.010 | |
rioxxterms.type | Other | |
herts.preservation.rarelyaccessed | true | |