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dc.contributor.authorGue, Ying X.
dc.contributor.authorJeong, Young-Hoon
dc.contributor.authorFarag, Mohamed
dc.contributor.authorSpinthakis, Nikolaos
dc.contributor.authorGorog, Diana
dc.date.accessioned2021-05-21T16:30:01Z
dc.date.available2021-05-21T16:30:01Z
dc.date.issued2021-03-01
dc.identifier.citationGue , Y X , Jeong , Y-H , Farag , M , Spinthakis , N & Gorog , D 2021 , ' Precision treatment in ACS – role of assessing fibrinolysis ' , Journal of Clinical Medicine , vol. 10 , no. 5 , 929 . https://doi.org/10.3390/jcm10050929
dc.identifier.issn2077-0383
dc.identifier.otherPURE: 24657490
dc.identifier.otherPURE UUID: 9099e8a4-33f2-47fe-9f84-d5c02a2bbac0
dc.identifier.otherScopus: 85114069576
dc.identifier.urihttp://hdl.handle.net/2299/24521
dc.description© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
dc.description.abstractDespite advancements in pharmacotherapy and interventional strategies, patients with acute coronary syndrome (ACS) remain at risk of recurrent thrombotic events. In addition to an enhanced tendency to thrombus formation, impairment in the ability to naturally dissolve or lyse a developing thrombus, namely impaired endogenous fibrinolysis, is responsible for a major part of this residual risk regardless of optimal antiplatelet medication. Global assessment of endogenous fibrinolysis, including a point-of-care assay, can identify patients with ACS at persistent high cardiovascular risk and might play an important role in allowing the personalisation of potent antithrombotic therapy to enhance fibrinolytic status, providing precision treatment of ACS to improve long-term outcome.en
dc.format.extent8
dc.language.isoeng
dc.relation.ispartofJournal of Clinical Medicine
dc.titlePrecision treatment in ACS – role of assessing fibrinolysisen
dc.contributor.institutionDepartment of Clinical, Pharmaceutical and Biological Science
dc.contributor.institutionBasic and Clinical Science Unit
dc.contributor.institutionCentre for Health Services and Clinical Research
dc.contributor.institutionSchool of Life and Medical Sciences
dc.description.statusPeer reviewed
rioxxterms.versionVoR
rioxxterms.versionofrecordhttps://doi.org/10.3390/jcm10050929
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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