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dc.contributor.authorChiappini, Stefania
dc.contributor.authorMosca, Alessio
dc.contributor.authorMiuli, A.
dc.contributor.authorSantovito, Monica Chiara
dc.contributor.authorOrsolini, Laura
dc.contributor.authorCorkery, John Martin
dc.contributor.authorGuirguis, Amira
dc.contributor.authorPettorruso, Mauro
dc.contributor.authorMartinotti, Giovanni
dc.contributor.authordi Giannantonio, Massimo
dc.contributor.authorSchifano, Fabrizio
dc.date.accessioned2021-06-07T13:00:03Z
dc.date.available2021-06-07T13:00:03Z
dc.date.issued2021-06-06
dc.identifier.citationChiappini , S , Mosca , A , Miuli , A , Santovito , M C , Orsolini , L , Corkery , J M , Guirguis , A , Pettorruso , M , Martinotti , G , di Giannantonio , M & Schifano , F 2021 , ' New Psychoactive Substances and suicidality: a systematic review of the current literature. ' , Medicina , vol. 57 , no. 6 , 1214747 . https://doi.org/10.3390/medicina57060580
dc.identifier.issn1010-660X
dc.identifier.otherPURE: 25367286
dc.identifier.otherPURE UUID: 158153b0-f4bb-4932-a21c-93c8e3a5e2db
dc.identifier.otherScopus: 85108338812
dc.identifier.urihttp://hdl.handle.net/2299/24559
dc.descriptionSubmitted 23 April 2021. Minor revisions requested 31 May 2021. Revisions submitted 3 June 2021. Accepted 3 June 2021. Epub 6 June 2021.
dc.description.abstractBackground and Objectives: Over the past twenty years a large number of New Psychoactive Substances (NPS) has entered and modified the recreational drug scene. Their intake has been associated with health-related risks, and especially so for vulnerable populations such as people with severe mental illness, who might be at higher risk of suicidality or self- injurious behaviour. This paper aims at providing an overview of NPS abuse and effects on mental health and suicidality issues, performing a literature review of the current related knowledge, thereby identifying substances that more than others are linked to suicidal behaviours. Materials and Methods: A comprehensive and updated overview of the literature regarding suicidality and NPS categories has been provided. An electronic search was performed, including all papers published up to March 2021, using the following keywords "NPS" OR "new psychoactive substances" OR "novel psychoactive substances" OR "synthetic cannabinoids" OR "phenethylamines" OR "synthetic cathinones" OR “tryptamines” OR “piperazines” OR “new synthetic opioids” OR “designer benzodiazepines”) AND ("suicide" OR "suicidality") NOT review NOT animal on the PubMed, Cochrane Library, and Web of Science online databases. Results: Suicidality and self-injurious behaviour appear to be frequently associated with some NPS such as cathinones, synthetic cannabinoids, and new synthetic opioids. Results are organised according to substances recorded. Conclusion: The growing use of NPS has become a significant clinical issue, posing increasing concern and challenges for clinicians working in both mental health and emergency departments. Thus, considering the associations between NPS and suicidality or self-injurious behaviours, areas where suicide-prevention efforts and strategies might be focused are the early detection, monitoring and restriction of NPS.en
dc.format.extent23
dc.language.isoeng
dc.relation.ispartofMedicina
dc.subjectNew Psychoactive Substances
dc.subjectNPS
dc.subjectSuicide
dc.subjectSuicidality
dc.subjectSynthetic cannabinoids
dc.subjectSynthetic cathinones
dc.subjectNew synthetic opioids
dc.titleNew Psychoactive Substances and suicidality: a systematic review of the current literature.en
dc.contributor.institutionDepartment of Clinical, Pharmaceutical and Biological Science
dc.contributor.institutionCentre for Health Services and Clinical Research
dc.contributor.institutionPsychopharmacology, Drug Misuse and Novel Psychoactive Substances Unit
dc.contributor.institutionSchool of Life and Medical Sciences
dc.description.statusPeer reviewed
rioxxterms.versionVoR
rioxxterms.versionofrecordhttps://doi.org/10.3390/medicina57060580
rioxxterms.typeOther
herts.preservation.rarelyaccessedtrue


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