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dc.contributor.authorDaneshvarhashjin , Nazanin
dc.contributor.authorChizari, Mahmoud
dc.contributor.authorMortazavi , Javad
dc.contributor.authorRouhi , Gholamreza
dc.date.accessioned2021-06-21T11:00:01Z
dc.date.available2021-06-21T11:00:01Z
dc.date.issued2021-06-18
dc.identifier.citationDaneshvarhashjin , N , Chizari , M , Mortazavi , J & Rouhi , G 2021 , ' Can the body slope of interference screw affect initial stability of reconstructed anterior cruciate ligament?: An in-vitro investigation ' , BMC Musculoskeletal Disorders , vol. 22 , no. 1 , 556 . https://doi.org/10.1186/s12891-021-04446-8
dc.identifier.issn1471-2474
dc.identifier.otherPURE: 25403573
dc.identifier.otherPURE UUID: 19ea0693-0c9a-4e30-b7d2-d2006443e4c4
dc.identifier.otherORCID: /0000-0003-0555-1242/work/96101787
dc.identifier.otherScopus: 85108120089
dc.identifier.urihttp://hdl.handle.net/2299/24597
dc.description© The Author(s). 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License. https://creativecommons.org/licenses/by/4.0/
dc.description.abstractBackground: Superior biomechanical performance of tapered interference screws, compared with non-tapered screws, with reference to the anterior cruciate ligament (ACL) reconstruction process, has been reported in the literature. However, the effect of tapered interference screw’s body slope on the initial stability of ACL is poorly understood. Thus, the main goal of this study was to investigate the effect of the interference screw's body slope on the initial stability of the reconstructed ACL. Methods: Based on the best screw-bone tunnel diameter ratios in non-tapered screws, two different tapered interference screws were designed and fabricated. The diameters of both screws were equal to bone tunnel diameter in one-third of their length from screw tip, then they were gradually increased by 1mm, in the lower slope (LSTIS), and 2 mm, in the higher slope (HSTIS) screws. To simulate the ACL reconstruction, sixteen soft tissue grafts were fixed, using HSTIS and LSTIS, in synthetic bone blocks. Through applying sub-failure cyclic incremental tensile load, graft-bone-screw construct's stiffness and graft laxity in each cycle, also through applying subsequent step of loading graft to the failure, maximum load to failure, and graft’s mode of failure were determined. Accordingly, the performance of the fabricated interference screws was compared with each other. Results: HSTIS provides a greater graft-bone-screw construct stiffness, and a lower graft laxity, compared to LSTIS. Moreover, transverse rupture of graft fibers for LSTIS, and necking of graft in the HSTIS group were the major types of grafts' failure. Conclusion: HSTIS better replicates the intact ACL's behavior, compared to LSTIS, by causing less damage in graft's fibers; reducing graft laxity; and increasing fixation stability. Nonetheless, finding the optimal slope remains as an unknown and can be the subject of future studies.en
dc.format.extent10
dc.language.isoeng
dc.relation.ispartofBMC Musculoskeletal Disorders
dc.rightsOpen
dc.titleCan the body slope of interference screw affect initial stability of reconstructed anterior cruciate ligament?: An in-vitro investigationen
dc.contributor.institutionCentre for Engineering Research
dc.contributor.institutionEnergy and Sustainable Design
dc.contributor.institutionCentre for Climate Change Research
dc.contributor.institutionSchool of Physics, Engineering & Computer Science
dc.contributor.institutionDepartment of Engineering and Technology
dc.contributor.institutionCentre for Future Societies Research
dc.description.statusPeer reviewed
dc.relation.schoolSchool of Physics, Engineering & Computer Science
dc.description.versiontypeFinal Published version
dcterms.dateAccepted2021-06-18
rioxxterms.versionVoR
rioxxterms.versionofrecordhttps://doi.org/10.1186/s12891-021-04446-8
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue
herts.rights.accesstypeOpen


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