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dc.contributor.authorOkeleke, Rosetta
dc.contributor.authorAslanpour, Zoe
dc.contributor.authorDhillon, Soraya
dc.contributor.authorUmaru, Nikkie
dc.date.accessioned2021-07-30T13:07:02Z
dc.date.available2021-07-30T13:07:02Z
dc.date.issued2021-06-23
dc.identifier.citationOkeleke , R , Aslanpour , Z , Dhillon , S & Umaru , N 2021 , ' Medicines Related Problems (MRPs) originating in Primary care settings in Older Adults - A Systematic Review ' , Journal of Pharmacy Practice . https://doi.org/10.1177/08971900211023638
dc.identifier.issn1531-1937
dc.identifier.otherPURE: 25252276
dc.identifier.otherPURE UUID: 5ccecd25-b784-4593-8f70-46463bff34af
dc.identifier.otherScopus: 85108594514
dc.identifier.urihttp://hdl.handle.net/2299/24933
dc.description© The Author(s) 2021. This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/)
dc.description.abstractBackground: As people age, they become increasingly vulnerable to the untoward effects of medicines due to changes in body systems. These may result in medicines related problems (MRPs) and consequent decline or deterioration in health. Aim: To identify MRPs, indicators of deterioration associated with these MRPs, and preventative interventions from the literature. Design and Setting: Systematic review of primary studies on MRPs originating in Primary Care in older people. Methods: Relevant studies published between 2001 and April 2018 were obtained from Medline (via PubMed), CINAHL, Embase, Psych Info, PASCAL, Scopus, Cochrane Library, Science Direct, and Zetoc. Falls, delirium, pressure ulcer, hospitalization, use of health services and death were agreed indicators of deterioration. The methodological quality of included studies was assessed using the Down and Black tool. Results: There were 1858 articles retrieved from the data bases. Out of these, 21 full text articles met inclusion criteria for the review. MRPs identified were medication error, potentially inappropriate medicines, adverse drug reaction and non-adherence. These were associated with indicators of deterioration. Interventions that involved doctors, pharmacists and patients in planning and implementation yielded benefits in halting MRPs. Conclusion: This Systematic review summarizes MRPs and associated indicators of deterioration. Appropriate interventions appeared to be effective against certain MRPs and their consequences. Further studies to explore deterioration presented in this systematic review is imperative.en
dc.format.extent13
dc.language.isoeng
dc.relation.ispartofJournal of Pharmacy Practice
dc.subjectOlder persons
dc.subjectPharmaceutical care issues
dc.subjectOlder persons, Primary health care
dc.subjectMRPs
dc.subjectGeriatrics
dc.subjectgeriatrics
dc.subjectprimary health care
dc.subjectpharmaceutical care issues
dc.subjectolder persons
dc.subjectPharmacology (medical)
dc.subjectPharmacy
dc.titleMedicines Related Problems (MRPs) originating in Primary care settings in Older Adults - A Systematic Reviewen
dc.contributor.institutionUniversity of Hertfordshire
dc.contributor.institutionCentre for Future Societies Research
dc.contributor.institutionDepartment of Clinical, Pharmaceutical and Biological Science
dc.contributor.institutionPublic Health and Patient Safety Unit
dc.contributor.institutionCentre for Health Services and Clinical Research
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionWeight and Obesity Research Group
dc.description.statusPeer reviewed
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85108594514&partnerID=8YFLogxK
rioxxterms.versionVoR
rioxxterms.versionofrecordhttps://doi.org/10.1177/08971900211023638
rioxxterms.typeOther
herts.preservation.rarelyaccessedtrue


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