dc.contributor.author | Farag, Mohamed | |
dc.contributor.author | Peverelli, Marta | |
dc.contributor.author | Spinthakis, Nikolaos | |
dc.contributor.author | Gue, Ying X. | |
dc.contributor.author | Egred, Mohaned | |
dc.contributor.author | Gorog, Diana | |
dc.date.accessioned | 2021-08-05T15:15:00Z | |
dc.date.available | 2021-08-05T15:15:00Z | |
dc.date.issued | 2021-07-10 | |
dc.identifier.citation | Farag , M , Peverelli , M , Spinthakis , N , Gue , Y X , Egred , M & Gorog , D 2021 , ' Spontaneous reperfusion in patients with transient ST-elevation myocardial infarction - prevalence, importance and approaches to management ' , Cardiovascular Drugs and Therapy . https://doi.org/10.1007/s10557-021-07226-7 | |
dc.identifier.issn | 0920-3206 | |
dc.identifier.uri | http://hdl.handle.net/2299/24960 | |
dc.description | © 2021 Springer Nature Switzerland AG. Part of Springer Nature. This is the accepted manuscript version of an article which has been published in final form at https://doi.org/10.1007/s10557-021-07226-7 | |
dc.description.abstract | Patients with transient ST-elevation myocardial infarction (STEMI) or spontaneous resolution (SpR) of the ST-segment elevation on electrocardiogram could potentially represent a unique group of patients posing a therapeutic management dilemma. In this review, we discuss the potential mechanisms underlying SpR, its relation to clinical outcomes and the proposed management options for patients with transient STEMI with a focus on immediate versus early percutaneous coronary intervention. We performed a structured literature search of PubMed and Cochrane Library databases from inception to December 2020. Studies focused on SpR in patients with acute coronary syndrome were selected. Available data suggest that deferral of angiography and revascularisation within 24-48 hours in these patients is reasonable and associated with similar or perhaps better outcomes than immediate angiography. Further randomized trials are needed to elucidate the best pharmacological and invasive strategies for this cohort. | en |
dc.format.extent | 34 | |
dc.format.extent | 4050781 | |
dc.language.iso | eng | |
dc.relation.ispartof | Cardiovascular Drugs and Therapy | |
dc.title | Spontaneous reperfusion in patients with transient ST-elevation myocardial infarction - prevalence, importance and approaches to management | en |
dc.contributor.institution | Centre for Health Services and Clinical Research | |
dc.contributor.institution | Basic and Clinical Science Unit | |
dc.contributor.institution | School of Life and Medical Sciences | |
dc.contributor.institution | Department of Clinical, Pharmaceutical and Biological Science | |
dc.description.status | Peer reviewed | |
dc.date.embargoedUntil | 2022-07-10 | |
rioxxterms.versionofrecord | 10.1007/s10557-021-07226-7 | |
rioxxterms.type | Journal Article/Review | |
herts.preservation.rarelyaccessed | true | |