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dc.contributor.authorSinclair, Jonathan
dc.contributor.authorShadwell, Gareth
dc.contributor.authorDillon, Stephanie
dc.contributor.authorAllan, Robert
dc.contributor.authorButters, Bobbie
dc.contributor.authorBottoms, Lindsay
dc.date.accessioned2021-09-22T12:25:03Z
dc.date.available2021-09-22T12:25:03Z
dc.date.issued2021-09-16
dc.identifier.citationSinclair , J , Shadwell , G , Dillon , S , Allan , R , Butters , B & Bottoms , L 2021 , ' Effects of Montmorency tart cherry and blueberry juice on cardiometabolic outcomes in healthy individuals: protocol for a 3-arm placebo randomized controlled trial ' , International Journal of Environmental Research and Public Health (IJERPH) , vol. 18 , no. 18 , 9759 . https://doi.org/10.3390/ijerph18189759
dc.identifier.issn1661-7827
dc.identifier.otherORCID: /0000-0003-4632-3764/work/100505997
dc.identifier.urihttp://hdl.handle.net/2299/25068
dc.description© This is an open access article distributed under the Creative Commons Attribution License. https://creativecommons.org/licenses/by/4.0/
dc.description.abstractCardiometabolic disease is recognized as the predominant cause of global mortality and healthcare expenditure. Whilst pharmaceutical interventions are effective in the short term, their long-term efficacy remain equivocal and their associated side-effects are concerning. Owing to their high levels of anthocyanins, Montmorency tart cherries and blueberries have been cited as potentially important natural treatment/preventative modalities for cardiometabolic disease. This study proposed a randomized controlled trial, aims to test the effects of consumption of Montmorency tart cherry and blueberry juice on cardiometabolic outcomes compared to placebo. This 20-day, parallel, single-blind, randomized, placebo-controlled trial will recruit 45 individuals, who will be assigned to receive 60 mL per day of either Montmorency tart cherry juice, blueberry juice or a cherry/blueberry flavoured placebo. The primary study outcome is the between-group difference in systolic blood pressure from baseline to post-intervention. Secondary outcome measures will be between-group differences in anthropometric, energy expenditure and substrate oxidation (during rest and physical activity), haematological, blood pressure/resting heart rate, psychological wellbeing and sleep efficacy indices. Statistical analysis will be conducted on an intention-to-treat basis. This study has been granted ethical approval by the University of Central Lancashire, Health Research Ethics Committee (ref: HEALTH 0016) and formally registered as a trial. Dissemination of the study findings from this investigation will be through publication in a leading peer-reviewed journal.en
dc.format.extent11
dc.format.extent652587
dc.language.isoeng
dc.relation.ispartofInternational Journal of Environmental Research and Public Health (IJERPH)
dc.subjectBlood pressure
dc.subjectBlueberry
dc.subjectCardiovascular disease
dc.subjectMetabolic health
dc.subjectTart cherry
dc.subjectPollution
dc.subjectPublic Health, Environmental and Occupational Health
dc.subjectHealth, Toxicology and Mutagenesis
dc.titleEffects of Montmorency tart cherry and blueberry juice on cardiometabolic outcomes in healthy individuals: protocol for a 3-arm placebo randomized controlled trialen
dc.contributor.institutionCentre for Research in Psychology and Sport Sciences
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionDepartment of Psychology, Sport and Geography
dc.contributor.institutionCentre for Applied Clinical, Health and Care Research (CACHE)
dc.contributor.institutionCentre for Future Societies Research
dc.contributor.institutionHigh Performance Sport Research Group
dc.contributor.institutionExercise, Health and Wellbeing Research Group
dc.description.statusPeer reviewed
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85114939838&partnerID=8YFLogxK
rioxxterms.versionofrecord10.3390/ijerph18189759
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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