dc.contributor.author | Tidmas, Victoria | |
dc.contributor.author | Brazier, Jon | |
dc.contributor.author | Bottoms, Lindsay | |
dc.contributor.author | Muniz, Daniel | |
dc.contributor.author | Desai, Terun | |
dc.contributor.author | Hawkins, Janine | |
dc.contributor.author | Sridharan, Sivakumar | |
dc.contributor.author | Farrington, Kenneth | |
dc.date.accessioned | 2022-12-15T16:00:01Z | |
dc.date.available | 2022-12-15T16:00:01Z | |
dc.date.issued | 2022-12-15 | |
dc.identifier.citation | Tidmas , V , Brazier , J , Bottoms , L , Muniz , D , Desai , T , Hawkins , J , Sridharan , S & Farrington , K 2022 , ' Ultra-endurance Participation and Acute Kidney Injury: A Narrative Review ' , International Journal of Environmental Research and Public Health (IJERPH) , vol. 19 , no. 24 . https://doi.org/10.3390/ijerph192416887 | |
dc.identifier.issn | 1661-7827 | |
dc.identifier.uri | http://hdl.handle.net/2299/25958 | |
dc.description | © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). | |
dc.description.abstract | Increasingly popular, ultra-endurance participation exposes athletes to extremely high levels of functional and structural damage. Ultra-endurance athletes commonly develop acute kidney in-jury (AKI) and other pathologies harmful to kidney health. There is strong evidence that non-steroidal anti-inflammatory drugs, common amongst ultra-athletes, is linked to increased risk and severity of AKI and potentially ischaemic renal injury, i.e., acute tubular necrosis. Ultra-endurance participation also increases the risk of exertional rhabdomyolysis, exercise-associated hyponatremia, and gastrointestinal symptoms, interlinked pathologies all with potential to increase the risk of AKI. Hydration and fuelling both also play a role with the development of multiple pathologies and ultimately AKI, highlighting the need for individualised nutritional and hydration plans to promote athlete health. Faster athletes, supplementing nitrates, and being female also increase the risk of developing AKI in this setting. Serum creatinine criteria do not provide the best indicator for AKI for ultra-athletes therefore further investigations are needed to assess the practicality and accuracy of new renal biomarkers such as neutrophil gelatinase-associated lipocalin (NGAL). The potential of recurring episodes of AKI provide need for further research to assess the longitudinal renal health impact of ultra-participation to provide appropriate advice to athletes, coaches, medical staff, and event organisers. | en |
dc.format.extent | 21 | |
dc.format.extent | 550166 | |
dc.language.iso | eng | |
dc.relation.ispartof | International Journal of Environmental Research and Public Health (IJERPH) | |
dc.title | Ultra-endurance Participation and Acute Kidney Injury: A Narrative Review | en |
dc.contributor.institution | School of Life and Medical Sciences | |
dc.contributor.institution | Centre for Research in Psychology and Sport Sciences | |
dc.contributor.institution | Department of Psychology, Sport and Geography | |
dc.contributor.institution | Centre for Future Societies Research | |
dc.contributor.institution | Psychology and NeuroDiversity Applied Research Unit | |
dc.contributor.institution | Health Research Methods Unit | |
dc.contributor.institution | Centre for Health Services and Clinical Research | |
dc.contributor.institution | Department of Clinical, Pharmaceutical and Biological Science | |
dc.contributor.institution | Basic and Clinical Science Unit | |
dc.contributor.institution | Centre for Applied Clinical, Health and Care Research (CACHE) | |
dc.contributor.institution | High Performance Sport Research Group | |
dc.contributor.institution | Exercise, Health and Wellbeing Research Group | |
dc.description.status | Peer reviewed | |
rioxxterms.versionofrecord | 10.3390/ijerph192416887 | |
rioxxterms.type | Other | |
herts.preservation.rarelyaccessed | true | |