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dc.contributor.authorHuang, Junjie
dc.contributor.authorChan, Erica On-Ting
dc.contributor.authorLiu, Xianjing
dc.contributor.authorLok, Veeleah
dc.contributor.authorNgai, Chun Ho
dc.contributor.authorZhang, Lin
dc.contributor.authorXu, Wanghong
dc.contributor.authorZheng, Zhi-Jie
dc.contributor.authorChiu, Peter Ka-Fung
dc.contributor.authorVasdev, Nikhil
dc.contributor.authorEnikeev, Dmitry
dc.contributor.authorShariat, Shahrokh F.
dc.contributor.authorNg, Chi-Fai
dc.contributor.authorTeoh, Jeremy Yuen-Chun
dc.contributor.authorWong, Martin CS
dc.date.accessioned2023-05-17T11:30:01Z
dc.date.available2023-05-17T11:30:01Z
dc.date.issued2023-08-30
dc.identifier.citationHuang , J , Chan , E O-T , Liu , X , Lok , V , Ngai , C H , Zhang , L , Xu , W , Zheng , Z-J , Chiu , P K-F , Vasdev , N , Enikeev , D , Shariat , S F , Ng , C-F , Teoh , J Y-C & Wong , M CS 2023 , ' Global Trends of Prostate Cancer by Age, and Their Associations with Gross Domestic Product (GDP), Human Development Index (HDI), Smoking, and Alcohol Drinking ' , Clinical Genitourinary Cancer , vol. 21 , no. 4 , pp. e261-e270 . https://doi.org/10.1016/j.clgc.2023.02.003
dc.identifier.issn1558-7673
dc.identifier.otherJisc: 910222
dc.identifier.otherJisc: 910222
dc.identifier.otherJisc: 1226582
dc.identifier.urihttp://hdl.handle.net/2299/26340
dc.description© 2023 Elsevier Inc. All rights reserved. This is the accepted manuscript version of an article which has been published in final form at https://doi.org/10.1016/j.clgc.2023.02.003
dc.description.abstractBackground: We aimed to examine the global disease burden and trends of prostate cancer incidence and mortality by age, and their associations with gross domestic product (GDP), human development index (HDI), smoking, and alcohol drinking. Materials and Methods: We retrieved the Global Cancer Observatory (GLOBOCAN) database for the incidence and mortality of prostate cancer in 2020; the World Bank for GDP per capita; the United Nations for HDI; the WHO Global Health Observatory for prevalence of smoking and alcohol drinking; the Cancer Incidence in 5 Continents (CI5), WHO mortality database, for trend analysis. We presented the prostate cancer incidence and mortality using age-standardized rates. We examined their associations with GDP, HDI, smoking, and alcohol drinking by Spearman's correlations and multivariable regression. We estimated the 10-year trend of incidence and mortality by joinpoint regression analysis with average annual percent change with 95% confidence intervals in different age groups. Results: A wide variation in the burden of prostate cancer with the highest mortality found in low-income countries while the highest incidence was observed in high-income countries. We found moderate to high positive correlations for GDP, HDI, and alcohol drinking with prostate cancer incidence, whilst a low negative correlation was observed for smoking. Globally, there was an increasing incidence but decreasing mortality of prostate cancer, and such trends were particularly prominent in Europe. Notably, the incidence increase was also found in the younger population ageden
dc.format.extent1332338
dc.language.isoeng
dc.relation.ispartofClinical Genitourinary Cancer
dc.subjectEpidemiology
dc.subjectIncidence
dc.subjectMortality
dc.subjectRisk factors
dc.subjectTemporal trend
dc.subjectOncology
dc.subjectUrology
dc.titleGlobal Trends of Prostate Cancer by Age, and Their Associations with Gross Domestic Product (GDP), Human Development Index (HDI), Smoking, and Alcohol Drinkingen
dc.contributor.institutionDepartment of Clinical, Pharmaceutical and Biological Science
dc.contributor.institutionExtracellular Vesicle Research Unit
dc.contributor.institutionBasic and Clinical Science Unit
dc.contributor.institutionCentre for Health Services and Clinical Research
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionCentre for Engineering Research
dc.description.statusPeer reviewed
dc.date.embargoedUntil2024-02-15
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85149675983&partnerID=8YFLogxK
rioxxterms.versionofrecord10.1016/j.clgc.2023.02.003
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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