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dc.contributor.authorGorog, Diana
dc.contributor.authorYamamoto, Junichiro
dc.date.accessioned2023-10-18T09:45:02Z
dc.date.available2023-10-18T09:45:02Z
dc.date.issued2023-11-23
dc.identifier.citationGorog , D & Yamamoto , J 2023 , ' Global Thrombosis Test: Occlusion Is Attributable to Shear-Induced Platelet Thrombus Formation ' , TH Open , vol. 5 , no. 4 , pp. e591-597 . https://doi.org/10.1055/a-1704-1022
dc.identifier.issn2512-9465
dc.identifier.urihttp://hdl.handle.net/2299/26937
dc.description© 2021 The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY), https://creativecommons.org/licenses/by/4.0/
dc.description.abstractWe read the paper by Clavería and co-workers with interest.1We strongly believe that the conclusions of their paper, suggesting that occlusion (occlusion time (OT)) in the global thrombosis test (GTT) is due to coagulation, rather than shear-induced platelet thrombus formation, is wrong and the evidence and arguments they present are fundamentally flawed. The authors have made major errors both in the approach to their experiments and in their interpretations of their results. The evidence which they demonstrate, shows that occlusion in the GTT is, in fact, caused by high shear-induced platelet thrombus formation, the complete opposite to their interpretation of their results. We set out below the evidence for that.en
dc.format.extent7
dc.format.extent263184
dc.language.isoeng
dc.relation.ispartofTH Open
dc.titleGlobal Thrombosis Test: Occlusion Is Attributable to Shear-Induced Platelet Thrombus Formationen
dc.contributor.institutionCentre for Health Services and Clinical Research
dc.contributor.institutionBasic and Clinical Science Unit
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionDepartment of Clinical, Pharmaceutical and Biological Science
dc.description.statusPeer reviewed
rioxxterms.versionofrecord10.1055/a-1704-1022
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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