| dc.contributor.author | Zhurakovskyi, Oleksandr | |
| dc.contributor.author | Türkmen, Yunus E | |
| dc.contributor.author | Löffler, Lorenz E | |
| dc.contributor.author | Moorthie, Vijayalakshmi A | |
| dc.contributor.author | Chen, C Chun | |
| dc.contributor.author | Shaw, Michael A | |
| dc.contributor.author | Crimmin, Mark R | |
| dc.contributor.author | Ferrara, Marco | |
| dc.contributor.author | Ahmad, Mushtaq | |
| dc.contributor.author | Ostovar, Mehrnoosh | |
| dc.contributor.author | Matlock, Johnathan V | |
| dc.contributor.author | Aggarwal, Varinder K | |
| dc.date.accessioned | 2023-10-20T16:15:01Z | |
| dc.date.available | 2023-10-20T16:15:01Z | |
| dc.date.issued | 2018-01-26 | |
| dc.identifier.citation | Zhurakovskyi , O , Türkmen , Y E , Löffler , L E , Moorthie , V A , Chen , C C , Shaw , M A , Crimmin , M R , Ferrara , M , Ahmad , M , Ostovar , M , Matlock , J V & Aggarwal , V K 2018 , ' Enantioselective Synthesis of the Cyclopiazonic Acid Family Using Sulfur Ylides ' , Angewandte Chemie International Edition , vol. 57 , no. 5 , pp. 1346-1350 . https://doi.org/10.1002/anie.201712065 | |
| dc.identifier.issn | 1433-7851 | |
| dc.identifier.other | PubMedCentral: PMC5817397 | |
| dc.identifier.uri | http://hdl.handle.net/2299/26960 | |
| dc.description | © 2018 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY), https://creativecommons.org/licenses/by/4.0/ | |
| dc.description.abstract | A convergent, nine-step (LLS), enantioselective synthesis of α-cyclopiazonic acid and related natural products is reported. The route features a) an enantioselective aziridination of an imine with a chiral sulfur ylide; b) a bioinspired (3+2)-cycloaddition of the aziridine onto an alkene; and c) installation of the acetyltetramic acid by an unprecedented tandem carbonylative lactamization/N-O cleavage of a bromoisoxazole. | en |
| dc.format.extent | 5 | |
| dc.format.extent | 3218277 | |
| dc.language.iso | eng | |
| dc.relation.ispartof | Angewandte Chemie International Edition | |
| dc.title | Enantioselective Synthesis of the Cyclopiazonic Acid Family Using Sulfur Ylides | en |
| dc.contributor.institution | School of Life and Medical Sciences | |
| dc.contributor.institution | Centre for Research in Mechanisms of Disease and Drug Discovery | |
| dc.description.status | Peer reviewed | |
| rioxxterms.versionofrecord | 10.1002/anie.201712065 | |
| rioxxterms.type | Journal Article/Review | |
| herts.preservation.rarelyaccessed | true | |
