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dc.contributor.authorMorgan, Marsha Y
dc.contributor.authorMadden, Angela M
dc.contributor.authorSoulsby, Clare T
dc.contributor.authorMorris, Richard W
dc.date.accessioned2009-01-27T11:58:57Z
dc.date.available2009-01-27T11:58:57Z
dc.date.issued2006
dc.identifier.citationMorgan , M Y , Madden , A M , Soulsby , C T & Morris , R W 2006 , ' Derivation and validation of a new global method for assessing nutritional status in patients with cirrhosis ' , Hepatology , vol. 44 , no. 4 , pp. 823-835 . https://doi.org/10.1002/hep.21358
dc.identifier.issn0270-9139
dc.identifier.otherPURE: 118319
dc.identifier.otherPURE UUID: 9561ef28-daf7-4e52-9685-31566f6d629f
dc.identifier.otherdspace: 2299/2846
dc.identifier.otherPubMed: 17006918
dc.identifier.otherScopus: 33750609857
dc.identifier.urihttp://hdl.handle.net/2299/2846
dc.description‘The definitive version is available at www3.interscience.wiley.com '. Copyright American Association for the Study of Liver Diseases / Wiley. DOI: 10.1002/hep.21358 [Full text of this article is not available in the UHRA]
dc.description.abstractAccurate assessments of nutritional status are difficult to obtain in patients with cirrhosis. The aim of this study was to devise and validate a global nutritional assessment scheme for use in this patient population. Measures of body mass index (BMI) and mid-arm muscle circumference (MAMC) were combined with details of dietary intake in a semistructured, algorithmic construct to provide a nutritional assessment scheme for use in patients with cirrhosis; evaluated individuals were classified as adequately nourished, moderately malnourished (or suspected to be), or severely malnourished. There was good interobserver agreement in the nutritional categorization of 50 patients with cirrhosis (34 men, 16 women) using this scheme (kappa = 0.79) and significant associations with the contributing objective variables--namely, BMI (Spearman's correlation r = -0.78; P <.001) and relative MAMC (r = -0.69; P <.001)--confirming its internal validity. There was a significant association between nutritional categorization in 20 patients with cirrhosis (10 men, 10 women) and estimates of total body protein obtained using a four-component model (r = -0.45; P = .046), confirming the external validity of the scheme. Finally, a significant association was found between poor nutritional status in 116 patients with cirrhosis (65 men, 51 women), followed for 14 to 52 months, and shorter subsequent survival (P = .0005), confirming the scheme's predictive validity. In conclusion, a global assessment scheme has been devised that provides a simple, reproducible, valid, and predictive method of assessing nutritional status in patients with cirrhosis.en
dc.format.extent13
dc.language.isoeng
dc.relation.ispartofHepatology
dc.subjectAdult
dc.subjectAged
dc.subjectAlgorithms
dc.subjectArm
dc.subjectBody Mass Index
dc.subjectEnergy Intake
dc.subjectFemale
dc.subjectHumans
dc.subjectLiver Cirrhosis
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectNutrition Disorders
dc.subjectNutritional Status
dc.subjectObserver Variation
dc.subjectReproducibility of Results
dc.subjectSkinfold Thickness
dc.titleDerivation and validation of a new global method for assessing nutritional status in patients with cirrhosisen
dc.contributor.institutionDepartment of Allied Health Professions and Midwifery
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.description.statusPeer reviewed
rioxxterms.versionofrecordhttps://doi.org/10.1002/hep.21358
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue
herts.rights.accesstyperestrictedAccess


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