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dc.contributor.authorCrow, T.J.
dc.contributor.authorDone, D.J.
dc.contributor.authorSacker, A.
dc.identifier.citationCrow , T J , Done , D J & Sacker , A 1996 , ' Cerebral lateralization is delayed in children who later develop schizophrenia ' , Schizophrenia Research , vol. 22 , no. 3 , pp. 181-185 .
dc.identifier.otherPURE: 189957
dc.identifier.otherPURE UUID: f332e538-8bda-4f5a-a055-da492eea5b3f
dc.identifier.otherdspace: 2299/3108
dc.identifier.otherScopus: 0030589704
dc.descriptionOriginal article can be found at: Copyright Elsevier. DOI: 10.1016/S0920-9964(96)00068-0 [Full text of this article is not available in the UHRA]
dc.description.abstractThe origins of schizophrenia are obscure. One suggestion is that it represents a component of the genetic variation associated with the establishment of dominance in one or other cerebral hemisphere, a mechanism that has been crucial in the evolution of language. Indices of cerebral hemispheric dominance (hand, foot and eye preference, speed of checking squares) recorded on the I6 980 children in the UK National Child Development Study cohort were examined in relation to psychiatric admission by the age of 28 years. Diagnoses were established by the application of Present State Examination criteria to case notes. Pre-schizophrenic children (n = 34−36) were more likely (p < 0.0003) to be rated by their mothers as ambidextrous at the age of 7 years, and at 11 years were less (p < 0.01) strongly right-handed than their peers in the cohort population on a test of relative hand skill: children who later developed affective psychosis (n=25) or neurosis (n=60) did not differ significantly from controls. Delay in establishing dominance in one hemisphere could be the critical factor that predisposes to schizophrenia.en
dc.relation.ispartofSchizophrenia Research
dc.titleCerebral lateralization is delayed in children who later develop schizophreniaen
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionDepartment of Psychology
dc.contributor.institutionCentre for Lifespan and Chronic Illness Research
dc.contributor.institutionHealth Services and Medicine
dc.contributor.institutionHealth and Clinical Psychology group
dc.description.statusPeer reviewed
rioxxterms.typeJournal Article/Review

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