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        Anti-BiP antibody levels in juvenile idiopathic arthritis (JIA)

        Author
        Bodman-Smith, M.D.
        Fife, M.F.
        Wythe, H.
        Corrigal, V.M.
        Panayi, G.S.
        Wedderburn, L.R.
        Woo, P.
        Attention
        2299/3386
        Abstract
        We have previously described the human heat shock protein BiP (immunoglobulin binding protein; glucose regulated protein 78) as an autoantigen in rheumatoid arthritis [1]. Antibodies to BiP have been described in the serum of RA patients by ourselves and other groups [2, 3] and we have recently described anti-BiP antibodies in the synovial fluid of RA patients and the serum of patients with primary Sjögren's syndrome [3]. Moreover anti-BiP antibodies have been shown to be elevated in animal models of arthritis [1].
        Publication date
        2004
        Published in
        Rheumatology
        Published version
        https://doi.org/10.1093/rheumatology/keh186
        Other links
        http://hdl.handle.net/2299/3386
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