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dc.contributor.authorRennie, K.L.
dc.contributor.authorHughes, J.
dc.contributor.authorLang, R.
dc.contributor.authorJebb, S.A.
dc.identifier.citationRennie , K L , Hughes , J , Lang , R & Jebb , S A 2003 , ' Nutritional management of rheumatoid arthritis: a review of the evidence ' , Journal of Human Nutrition and Dietetics , vol. 16 , no. 2 , pp. 97-109 .
dc.identifier.otherPURE: 119426
dc.identifier.otherPURE UUID: 06613f0c-7a76-4805-a762-28059fb9cdc9
dc.identifier.otherdspace: 2299/3669
dc.identifier.otherScopus: 0038414673
dc.description‘The definitive version is available at: '. Copyright Blackwell Publishing / British Dietetic Association. DOI: 10.1046/j.1365-277X.2003.00423.x [Full text of this article is not available in the UHRA]
dc.description.abstractRheumatoid arthritis (RA) is a debilitating disease and is associated with increased risk of cardiovascular disease and osteoporosis. Poor nutrient status in RA patients has been reported and some drug therapies, such as nonsteroidal anti-inflammatory drugs (NSAIDs), prescribed to alleviate RA symptoms, may increase the requirement for some nutrients and reduce their absorption. This paper reviews the scientific evidence for the role of diet and nutrient supplementation in the management of RA, by alleviating symptoms, decreasing progression of the disease or by reducing the reliance on, or combating the side-effects of, NSAIDs. Supplementation with long-chain n-3 polyunsaturated fatty acids (PUFA) consistently demonstrates an improvement in symptoms and a reduction in NSAID usage. Evidence relating to other fatty acids, antioxidants, zinc, iron, folate, other B vitamins, calcium, vitamin D and fluoride are also considered. The present evidence suggests that RA patients should consume a balanced diet rich in long-chain n-3 PUFA and antioxidants. More randomized long-term studies are needed to provide evidence for the benefits of specific nutritional supplementation and to determine optimum intake, particularly for n-3 PUFA and antioxidants.en
dc.relation.ispartofJournal of Human Nutrition and Dietetics
dc.titleNutritional management of rheumatoid arthritis: a review of the evidenceen
dc.contributor.institutionDepartment of Allied Health Professions and Midwifery
dc.description.statusPeer reviewed
rioxxterms.typeJournal Article/Review

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