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dc.contributor.authorChilcot, J.
dc.contributor.authorWellsted, D.
dc.contributor.authorVilar, Enric
dc.contributor.authorFarrington, Ken
dc.identifier.citationChilcot , J , Wellsted , D , Vilar , E & Farrington , K 2009 , ' An Association between Residual Renal Function and Depression Symptoms in Haemodialysis Patients ' , Nephron Clinical Practice , vol. 113 , no. 2 , pp. 117-124 .
dc.identifier.otherPURE: 117500
dc.identifier.otherPURE UUID: 0382269b-7b65-43e5-89c8-2aa8b97b13d3
dc.identifier.otherdspace: 2299/3828
dc.identifier.otherScopus: 67650705724
dc.descriptionOriginal article can be found at: Copyright Karger. [Full text of this article is not available in the UHRA]
dc.description.abstractBackground: The loss of residual renal function (RRF) and subsequent urine volume among haemodialysis (HD) patients may influence affect. Although RRF has been associated with improved patient outcome, its relationship with depression symptomatology is unknown. Methods: 106 HD patients completed the Beck Depression Inventory (BDI). The BDI is a depression symptom screening tool, with a score of 16 indicating possible clinical depression. Clinical parameters, including RRF (urea clearance, KRU [ml/min]) and interdialytic urine volume, were averaged over the 3-month pre-assessment including the month of the BDI assessment. Results: BDI scores correlated negatively with KRU and interdialytic urine volume. Patients with a KRU <1 had significantly higher BDI scores compared to those with a KRU 1. In logistic regression, KRU significantly predicted a BDI score 16, after controlling for a range of clinical parameters including urea, dialysis vintage and treatment time. A history of depressive illness was the only other predictive factor. Conclusion: We have demonstrated an association between RRF and depression symptoms in HD patients. The perception of loss associated with low RRF and urine volume may increase depressive vulnerability. Longitudinal assessment is required in order to validate this finding and to determine causality.en
dc.relation.ispartofNephron Clinical Practice
dc.titleAn Association between Residual Renal Function and Depression Symptoms in Haemodialysis Patientsen
dc.contributor.institutionDepartment of Psychology
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.contributor.institutionCentre for Postgraduate Medicine
dc.contributor.institutionCentre for Lifespan and Chronic Illness Research
dc.description.statusPeer reviewed
rioxxterms.typeJournal Article/Review

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