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dc.contributor.authorAl-Uzri, M.M.
dc.contributor.authorLaws, K.R.
dc.contributor.authorMortimer, A.M.
dc.date.accessioned2011-02-03T09:35:46Z
dc.date.available2011-02-03T09:35:46Z
dc.date.issued2004
dc.identifier.citationAl-Uzri , M M , Laws , K R & Mortimer , A M 2004 , ' An early marker for semantic memory impairment in patients with schizophrenia ' Cognitive Neuropsychiatry , vol. 9 , no. 4 , pp. 267-279 . https://doi.org/10.1080/13546800344000255
dc.identifier.issn1354-6805
dc.identifier.otherPURE: 194572
dc.identifier.otherPURE UUID: 8d76a0ad-60fd-45ae-a1e0-8547a29f026f
dc.identifier.otherdspace: 2299/5289
dc.identifier.otherScopus: 8644236460
dc.identifier.urihttp://hdl.handle.net/2299/5289
dc.descriptionOriginal article can be found at: http://www.informaworld.com Copyright Informa / Taylor and Francis Group [Full text of this article is not available in the UHRA]
dc.description.abstractIntroduction: Semantic memory impairment is now a well-documented phenomenon in patients with schizophrenia. Nevertheless, the characteristics of this deficit and any early markers remain contentious. Methods: In this preliminary study, 12 schizophrenic patients underwent longitudinal assessment using a battery of semantic memory tests. Patient performance was compared to 12 matched controls. Using set criteria (derived from Warrington & Shallice, 1979), we examined whether the patients had a disorder affecting access to intact representations, or a degradation/loss of the representations themselves. The criteria were: consistency across time and modality, level of attribute information, and responsiveness to cueing. Finally, we compared patient naming for the same items across two naming tests (naming-to-description and picture naming) to determine cross-modality consistency. Results: As expected, normal controls outperformed the patients on all tests. Naming-to-description was the most significant differentiator between patients and controls. Patients were inconsistent across both time and modality, showed minimal attributional knowledge impairment, and improved significantly with cueing on two naming tests. Conclusion: The profile of results indicates an access-type semantic deficit in this cohort of patients with schizophrenic. Finally, on a naming-to-description task, the patients failed to name up to 20% of items that they could name to picture. This suggests that naming-to-definition may act as an early marker of semantic memory impairment.en
dc.language.isoeng
dc.relation.ispartofCognitive Neuropsychiatry
dc.subjectPsychology
dc.titleAn early marker for semantic memory impairment in patients with schizophreniaen
dc.contributor.institutionDepartment of Psychology
dc.description.statusPeer reviewed
rioxxterms.versionofrecordhttps://doi.org/10.1080/13546800344000255
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue
herts.rights.accesstyperestrictedAccess


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