dc.contributor.author | Fry, A.C. | |
dc.contributor.author | Singh, S. | |
dc.contributor.author | Gunda, S.S. | |
dc.contributor.author | Boustead, G.B. | |
dc.contributor.author | Hanbury, D.C. | |
dc.contributor.author | McNicholas, T.A. | |
dc.contributor.author | Farrington, Ken | |
dc.date.accessioned | 2011-04-20T11:17:36Z | |
dc.date.available | 2011-04-20T11:17:36Z | |
dc.date.issued | 2008 | |
dc.identifier.citation | Fry , A C , Singh , S , Gunda , S S , Boustead , G B , Hanbury , D C , McNicholas , T A & Farrington , K 2008 , ' Successful use of steroids and ureteric stents in 24 patients with idiopathic retroperitoneal fibrosis : a retrospective study ' , Nephron Clinical Practice , vol. 108 , no. 3 , pp. 213-220 . https://doi.org/10.1159/000119715 | |
dc.identifier.issn | 1660-2110 | |
dc.identifier.other | dspace: 2299/5696 | |
dc.identifier.uri | http://hdl.handle.net/2299/5696 | |
dc.description | Original article can be found at : http://content.karger.com/ Copyright Karger [Full text of this article is not available in the UHRA] | |
dc.description.abstract | Background/Aims: Retroperitoneal fibrosis (RPF) is a chronic inflammatory disorder causing obstructive nephropathy and renal failure. We reviewed our management of this condition. Method: All patients with RPF treated at a single center over a 15-year period were identified. A full review of notes and computer records was undertaken. Results: Data was available on 27 patients, 3 of which were excluded from later analysis. Diagnosis was based on clinical history and cross-sectional imaging. Retroperitoneal biopsy was undertaken in 3 patients. 96% had significant renal impairment at presentation with a mean serum creatinine of 688 μmol/l. 46% required emergency hemodialysis. All patients were treated with a combination of ureteric stents and/or steroids with an excellent clinical response. The mean best creatinine reached by the cohort was 136 μmol/l, and renal function remained stable in the long term. No patients required chronic dialysis. Ureteric stents were removed within 12 months and low-dose steroids were continued for a mean of 34 months. Recurrent disease was observed in 25% of patients, who all responded well to further steroid therapy. Mean duration of follow-up was 76 months. Conclusions: RPF is very effectively treated by a combination of ureteric stents and steroids, with excellent long-term results using this approach. Continued follow-up is advised because of the possibility of recurrent disease. | en |
dc.format.extent | 164526 | |
dc.language.iso | eng | |
dc.relation.ispartof | Nephron Clinical Practice | |
dc.subject | retroperitoneal fibrosis | |
dc.subject | steroids | |
dc.subject | stents | |
dc.subject | ureterolysis | |
dc.subject | renal failure | |
dc.title | Successful use of steroids and ureteric stents in 24 patients with idiopathic retroperitoneal fibrosis : a retrospective study | en |
dc.contributor.institution | Centre for Postgraduate Medicine | |
dc.description.status | Peer reviewed | |
rioxxterms.versionofrecord | 10.1159/000119715 | |
rioxxterms.type | Journal Article/Review | |
herts.preservation.rarelyaccessed | true | |