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Browsing University of Hertfordshire by Author "Chiappini, Stefania"
Now showing items 21-38 of 38
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Ibogaine/Noribogaine in the treatment of Substance Use Disorders: a systematic review of the current literature
Mosca, Alessio; Chiappini, Stefania; Miuli, Andrea; Mancusi, Gianluca; Santovito, Maria Chiara; Di Carlo, Francesco; Pettorruso, Mauro; Corkery, John; Canessa, Carlos; Martinotti, Giovanni; Di Giannantonio, Massimo (2023-02-07)Background: Ibogaine and noribogaine are psychedelic substances with dissociative properties naturally occurring in plants of the Apocynaceae family. Research has shown their efficacy in treating substance use disorders ... -
An Insight into Z-Drug Abuse and Dependence : An Examination of Reports to the European Medicines Agency Database of Suspected Adverse Drug Reactions
Schifano, Fabrizio; Chiappini, Stefania; Corkery, John Martin; Guirguis, Amira (2019-04-01)BACKGROUND: Although originally marketed as safe alternatives to the habit-forming benzodiazepines, growing numbers of zaleplon, zolpidem, and zopiclone ("Z-drugs") clinical concerns relating to their potential of abuse, ... -
Investigating the effectiveness and tolerability of intranasal esketamine among older adults with treatment-resistant depression (TRD): a post-hoc analysis from the REAL-ESK study group
d’Andre, Giacomo; S. McIntyre, Roger; Chiappini, Stefania; Stefanelli, Giulia; Carullo, Rosalba; Andriola, Ileana; Zanardi, Raffaella; Martiadis, Vassillis; L. Sensi, Stefano; Sani, Gabriele; Clerici, Massimo; Di Lorenzo, Giorgio; Vita, Antonio; Pettorruso, Mauro; Martinotti, Giovanni (2023-07-08)Introduction: Treatment-resistant depression (TRD) is a serious and debilitating psychiatric disorder that frequently affects older patients. Esketamine nasal spray (ESK-NS) has recently been approved as a treatment for ... -
Is medicinal ketamine associated with urinary dysfunction issues? Assessment of both the European Medicines Agency (EMA) and the UK Yellow Card Scheme pharmacovigilance database-related reports
Schifano, Nicolo; Chiappini, Stefania; Castiglione, Fabio; Salonia, Andrea; Schifano, Fabrizio (2020-10-09)Objective - A range of associated urinary dysfunction (KIU) issues have been typically described in ketamine misusers. Conversely, more knowledge is needed in terms of medicinal ketamine-related urological disturbances. ... -
Is medicinal ketamine associated with urinary dysfunction issues? Assessment of both the European Medicines Agency (EMA) and the UK Yellow Card Scheme pharmacovigilance database-related reports
Schifano, Nicolo; Chiappini, Stefania; Castiglione, Fabio; Salonia, Andrea; Schifano, Fabrizio (2020-10-09)Objective: A range of ketamine-induced uropathy (KIU) issues have been typically described in ketamine misusers. Conversely, more knowledge is needed in terms of medicinal ketamine-related urological disturbances, since ... -
Is There a Potential of Misuse for Quetiapine?
Chiappini, Stefania; Schifano, Fabrizio (2018-02-01)Purpose/Background A recent years' increase in both prescribing and availability of second-generation antipsychotics (SGAs) has been observed. According to the literature, typically made up by case studies/series, quetiapine ... -
Is There a Risk for Semaglutide Misuse? Focus on the Food and Drug Administration’s FDA Adverse Events Reporting System (FAERS) Pharmacovigilance Dataset
Chiappini, Stefania; Vickers-Smith, Rachel; Harris, Daniel; Papanti Pelletier, G. Duccio; Corkery, John Martin; Guirguis, Amira; Martinotti, Giovanni; Sensi, Stefano L.; Schifano, Fabrizio (2023-07-11)Recent media reports commented about a possible issue of the misuse of antidiabetics related to molecules promoted as a weight-loss treatment in non-obese people. We evaluated here available pharmacovigilance misuse/abuse ... -
Misuse of anticholinergic medications: a systematic review.
Chiappini, Stefania; Mosca, Alessio; Miuli, Andrea; Semeraro, Francesco; Mancusi, Gianluca; Santovito, Maria Chiara; Di Carlo, Francesco; Pettorruso, Mauro; Guirguis, Amira; Corkery, John M.; Martinotti, Giovanni; Schifano, Fabrizio; di Giannantonio, Massimo (2022-02-01)(1) Background: Over the last decade, misuse and diversion of medications has appeared to be increasingly concerning phenomena, including a range of different molecules. As current knowledge on the abuse of centrally acting ... -
Misuse of prescription and over-the-counter drugs to obtain illicit highs: how pharmacists can prevent abuse
Chiappini, Stefania; Guirguis, Amira; Corkery, John; Schifano, Fabrizio (2020-11-18)There have been increasing reports of misuse of a range of prescription and over-the-counter (OTC) drugs for recreational purposes. The use of psychoactive pharmaceuticals and ‘pharming’ are new, widespread phenomena ... -
New Psychoactive Substances and suicidality: a systematic review of the current literature.
Chiappini, Stefania; Mosca, Alessio; Miuli, A.; Santovito, Monica Chiara; Orsolini, Laura; Corkery, John Martin; Guirguis, Amira; Pettorruso, Mauro; Martinotti, Giovanni; di Giannantonio, Massimo; Schifano, Fabrizio (2021-06-06)Background and Objectives: Over the past twenty years a large number of New Psychoactive Substances (NPS) has entered and modified the recreational drug scene. Their intake has been associated with health-related risks, ... -
New trends of drug abuse in custodial settings: a systematic review on the misuse of over-the-counter drugs, prescription-only-medications, and new psychoactive substances
Chiappini, Stefania; Vaccaro, Giorgia; Mosca, Alessio; Miuli, Andrea; Stigliano, Gianfranco; Stefanelli, Giulia; Giovannetti, Giulia; Carullo, Rosalba; d'Andrea, Giacomo; Di Carlo, Francesco; Cavallotto, Clara; Pettorruso, Mauro; Di Petta, Gilberto; Corkery, John Martin; Guirguis, Amira; Stair, Jacqueline L.; Martinotti, Giovanni; Fazel, Seena; Schifano, Fabrizio (2024-07-30)The article presents a systematic literature review on the use and the psychiatric implications of over-the-counter drugs (OTC), prescription-only-medications (POM), and new psychoactive substances (NPS) within custodial ... -
Pharmacovigilance Signals of the Opioid Epidemic over 10 Years: Data Mining Methods in the Analysis of Pharmacovigilance Datasets Collecting Adverse Drug Reactions (ADRs) Reported to EudraVigilance (EV) and the FDA Adverse Event Reporting System (FAERS)
Chiappini, Stefania; Vickers-Smith, Rachel; Guirguis, Amira; Corkery, John M.; Martinotti, Giovanni; Harris, Daniel R.; Schifano, Fabrizio (2022-05-27)In the past twenty years, the consumption of opioid medications has reached significant proportions, leading to a rise in drug misuse and abuse and increased opioid dependence and related fatalities. Thus, the purpose of ... -
Recreational Drug Misuse and Its Potential Contribution to Male Fertility Levels’ Decline: A Narrative Review
Schifano, Nicolò; Chiappini, Stefania; Mosca, Alessio; Miuli, Andrea; Santovito, Maria Chiara; Pettorruso, Mauro; Capogrosso, Paolo; Dehò, Federico; Martinotti, Giovanni; Schifano, Fabrizio (2022-11-19)Recreational drug intake may be associated with a range of medical untoward consequences, including male infertility. However, as the related evidence is still limited, the main outcome of this review is to provide a better ... -
Therapeutic Potentials of Ketamine and Esketamine in Obsessive–Compulsive Disorder (OCD), Substance Use Disorders (SUD) and Eating Disorders (ED): A Review of the Current Literature
Martinotti, Giovanni; Chiappini, Stefania; Pettorruso, Mauro; Mosca, Alessio; Miuli, Andrea; Di Carlo, Francesco; D’Andrea, Giacomo; Collevecchio, Roberta; Di Muzio, Ilenia; Sensi, Stefano L.; Di Giannantonio, Massimo (2021-06-27)The obsessive–compulsive spectrum refers to disorders drawn from several diagnostic categories that share core features related to obsessive–compulsive disorder (OCD), such as obsessive thoughts, compulsive behaviors and ... -
Treating bipolar depression with esketamine: Safety and effectiveness data from a naturalistic multicentric study on esketamine in bipolar versus unipolar treatment‐resistant depression
the REAL‐ESK Study Group; Martinotti, Giovanni; Dell'Osso, Bernardo; Di Lorenzo, Giorgio; Maina, Giuseppe; Bertolino, Alessandro; Clerici, Massimo; Barlati, Stefano; Rosso, Gianluca; Di Nicola, Marco; Marcatili, Matteo; d'Andrea, Giacomo; Cavallotto, Clara; Chiappini, Stefania; De Filippis, Sergio; Nicolò, Giuseppe; De Fazio, Pasquale; Andriola, Ileana; Zanardi, Raffaella; Nucifora, Domenica; Di Mauro, Stefania; Bassetti, Roberta; Pettorruso, Mauro; McIntyre, Roger S.; Sensi, Stefano L.; di Giannantonio, Massimo; Vita, Antonio; Baldacci, Giulia; Belletti, Sandro; Bellomo, Antonello; Benatti, Beatrice; Carminati, Matteo; Carullo, Rosalba; de Berardis, Domenico; de Filippis, Renato; Chiaie, Roberto Delle; di Carlo, Francesco; Di Petta, Gilberto; Galluzzo, Alessandro; Giorgelli, Valentina; Lombardozzi, Ginevra; Martiadis, Vassilis; Mattei, Chiara; Mosca, Alessio; Niolu, Cinzia; Olivola, Miriam; Percudani, Mauro; Pepe, Maria; Rossi, Eros; Scardigli, Maria Ilaria; Tatì, Filippo (2023-01-18)Background: Bipolar depression accounts for most of the disease duration in type I and type II bipolar disorder (BD), with few treatment options, often poorly tolerated. Many individuals do not respond to first‐line ... -
An update on psychoactive substances: Pharmacology and Toxicology issues
Chiappini, Stefania; Schifano, Fabrizio (2023-08-18) -
Use of Medicinal Cannabis and Synthetic Cannabinoids in Posttraumatic Stress Disorder (PTSD): a systematic review
Orsolini, Laura; Chiappini, Stefania; Volpe, Umberto; De Berardis, Domenico; Latini, Roberto; Papanti, Gabriele Duccio; Corkery, John (2019-08-23)Background and Objectives: Post-traumatic stress disorder (PTSD) is a common psychiatric disorder resulting from a traumatic event, is manifested through hyperarousal, anxiety, depressive symptoms, and sleep disturbances. ... -
What about “Pharming”? Issues Regarding the Misuse of Prescription and Over‐the‐Counter Drugs
Chiappini, Stefania; Schifano, Fabrizio (2020-10-14)Recently, a range of prescription and over‐the‐counter (OTC) drugs have emerged as being used recreationally, either on their own or in combination with other substances, both licit and illicit, including new psychoactive ...