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Browsing University of Hertfordshire by Author "Jones, Stuart A."
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Stabilisation of deoxyribonuclease in hydrofluoroalkanes using miscible vinyl polymers
Jones, Stuart A.; Martin, Gary P.; Brown, Marc (2006-09-28)A mix of biocompatible macromolecules (poly(vinyl alcohol) (PVA) and poly(vinyl pyrrolidone) (PVP)) has been shown previously to enhance the physical stability of non-aqueous pharmaceutical suspensions. The aim of this ... -
Tocopheryl acetate disposition in porcine and human skin when administered using lipid nanocarriers
Moddaresi, Mojgan; Brown, Marc; Tamburic, Slobodanka; Jones, Stuart A. (2010-06)Objectives: Assessing the delivery of a drug into the skin when it has been formulated within a nanocarrier is a complex process that does not conform to the conventions of traditional semi-solid formulations. The aim of ... -
Transient drug supersaturation kinetics of beclomethasone dipropionate in rapidly drying films
Reid, Monica L.; Jones, Stuart A.; Brown, Marc (2009-04-17)Supersaturation is an effective method to enhance the delivery of active compounds into the skin, however the long-term instability of the drug in these formulations that exceed thermodynamic unity prevents clinical use. ... -
Vinyl polymer-coated lorazepam particles for drug delivery to the airways
Traynor, M.J.; Zhao, Yanjun; Brown, Marc; Jones, Stuart A. (2011-05-30)A particle engineering method that adsorbs a microfine vinyl polymer coat to crystalline drug microparticles has been shown to be an effective way to control delivery. However, the means by which the functional performance ...