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Browsing University of Hertfordshire by Author "Bourne, Lucie E"
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2-oxothiazolidine-4-carboxylic acid inhibits vascular calcification via induction of glutathione synthesis
Patel, Jessal; Bourne, Lucie E; Thakur, Shori; Farrington, Kenneth; Gorog, Diana; Orriss, Isabel R; Baydoun, Anwar (2020-09-12)Arterial medial calcification (AMC), the deposition of hydroxyapatite in the medial layer of the arteries, is a known risk factor for cardiovascular events. Oxidative stress is a known inducer of AMC and endogenous ... -
Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts
Patel, Jessal; Bourne, Lucie E; Davies, Bethan K; Arnett, Timothy R; MacRae, Vicky E; Wheeler-Jones, Caroline P D; Orriss, Isabel R (2019-07-01)Arterial medial calcification (AMC) is the deposition of calcium phosphate mineral, often as hydroxyapatite, inthe medial layer of the arteries. AMC shares some similarities to skeletal mineralisation and has been ...