- UHRA Home
- University of Hertfordshire
- Browsing University of Hertfordshire by Author
Browsing University of Hertfordshire by Author "Crnogorac-Jurcevic, Tatjana"
Now showing items 1-3 of 3
-
A combination of urinary biomarker panel and PancRISK score for earlier detection of pancreatic cancer : A case-control study
Debernardi, Silvana; O'Brien, Harrison; Algahmdi, Asma S; Malats, Nuria; Stewart, Grant D; Plješa-Ercegovac, Marija; Costello, Eithne; Greenhalf, William; Saad, Amina; Roberts, Rhiannon; Ney, Alexander; Pereira, Stephen P; Kocher, Hemant M; Duffy, Stephen; Blyuss, Oleg; Crnogorac-Jurcevic, Tatjana (2020-12-10)BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with around 9% of patients surviving >5 years. Asymptomatic in its initial stages, PDAC is mostly diagnosed late, when already a locally ... -
Development of PancRISK, a urine biomarker-based risk score for stratified screening of pancreatic cancer patients
Blyuss, Oleg; Zaikin, Alexey; Cherepanova, Valeriia; Munblit, Daniel; Kiseleva, Elena M; Prytomanova, Olga M; Duffy, Stephen W; Crnogorac-Jurcevic, Tatjana (2019-12-20)BACKGROUND: An accurate and simple risk prediction model that would facilitate earlier detection of pancreatic adenocarcinoma (PDAC) is not available at present. In this study, we compare different algorithms of risk ... -
Discovery of novel small molecule inhibitors of S100P, with in vitro anti-metastatic effects on pancreatic cancer cells
Camara, Ramatoulie; Ogbeni, Deborah; Gerstmann, Lisa; Ostovar, Mehrnoosh; Hurer, Ellie; Scott, Mark; Mahmoud, Nasir; Radon, Tomasz; Crnogorac-Jurcevic, Tatjana; Patel, Pryank; Mackenzie, Louise Susan; Chau, David; Kirton, Stewart; Rossiter, Sharon (2020-10-01)S100P, a calcium- binding protein, is known to advance tumor progression and metastasis in pancreatic and several other cancers. Herein is described the in silico identification of a putative binding pocket of S100P to ...