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Browsing University of Hertfordshire by Author "Crompton, Tessa"
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Phosphorylation of NTRK1 at Y674/Y675 induced by TP53-dependent repression of PTPN6 expression : A potential novel prognostic marker for breast cancer
Youssef, Gehad; Gillet, Cheryl; Agbaje, Orunsola; Crompton, Tessa; Montano, Ximena (2014-03)We have identified a ligand-independent mechanism whereby the tumor suppressor, TP53, induces nerve growth factor receptor, NTRK1, phosphorylation at Y674/Y675 (NTRK1-pY674/pY675), via the repression of the NTRK1-phosphatase, ...