- UHRA Home
- University of Hertfordshire
- Browsing University of Hertfordshire by Author
Browsing University of Hertfordshire by Author "Dalton, Christopher H."
Now showing items 1-6 of 6
-
Absorption of the nerve agent VX (O-ethyl-S-[2(di-isopropylamino)ethyl] methyl phosphonothioate) through pig, human and guinea pig skin in vitro
Dalton, Christopher H.; Hattersley, Ian J.; Rutter, Stephen J.; Chilcott, Robert (2006-12)The physico-chemical properties of VX make the skin the most likely route of absorption into the human body. The development of effective medical countermeasures against such percutaneous threat agents relies on the use ... -
Development of haemostatic decontaminants for the treatment of wounds contaminated with chemical warfare agents. 1 : Evaluation of in vitro clotting efficacy in the presence of certain contaminants
Hall, Charlotte A.; Lydon, Helen L.; Dalton, Christopher H.; Chipman, J. Kevin; Graham, John S.; Chilcott, Robert (2015-05-01)The treatment of penetrating, haemorrhaging injuries sustained within a hazardous environment may be complicated by contamination with toxic chemicals. There are currently no specific medical countermeasures for such ... -
Development of haemostatic decontaminants for the treatment of wounds contaminated with chemical warfare agents. 2 : Evaluation of in vitro topical decontamination efficacy using undamaged skin
Dalton, Christopher H.; Hall, Charlotte A.; Lydon, Helen L.; Chipman, J. Kevin; Graham, John S.; Jenner, John; Chilcott, Robert (2015-05-23)The risk of penetrating, traumatic injury occurring in a chemically contaminated environment cannot be discounted. Should a traumatic injury be contaminated with a chemical warfare (CW) agent, it is likely that standard ... -
Development of haemostatic decontaminants for treatment of wounds contaminated with chemical warfare agents. 3: Evaluation of in vitro topical decontamination efficacy using damaged skin
Lydon, Helen L.; Hall, Charlotte A.; Dalton, Christopher H.; Chipman, J. Kevin; Graham, John S.; Chilcott, Robert (2017-06-13)Previous studies have demonstrated that haemostatic products with an absorptive mechanism of action retain their clotting efficiency in the presence of toxic materials and are effective in decontaminating chemical warfare ... -
Evaluation of barrier creams against sulphur mustard: (II) in vivo and in vitro studies using the domestic white pig
Chilcott, Robert; Dalton, Christopher H.; Ashley, Zoe; Allen, Ceri E.; Bradley, Simon T.; Maidment, Michael P.; Jenner, John; Brown, Roger F. R.; Gwyther, Robert J.; Rice, Paul (2007)Previous studies in our laboratory have demonstrated that barrier creams, comprising perfluorinated polymers, are effective against the chemical warfare agent sulphur mustard (SM) when evaluated using human skin in vitro. ... -
The in vitro efficacy of haemostatic products in the presence of chemical warfare agents-Sulphur mustard (HD) and VX
Hall, Charlotte A.; Lydon, Helen L.; Dalton, Christopher H.; Chipman, J. Kevin; Chilcott, Robert; Graham, John S. (2009-07-28)Haemorrhage remains to be a leading cause of death for trauma victims (Bellamy, 1984). Wound contamination poses an additional complication in the initial management of haemorrhaging wounds, with no specific medical treatment ...