Now showing items 1-5 of 5

    • Cloning and functional expression of a human orthologue of the rat vanilloid receptor-1 

      Hayes, P.; Meadows, H.J.; Gunthorpe, M.J.; Harries, M.; Duckworth, M.; Cairns, W.; Harrison, D. C.; Ellington, K.; Prinjha, R.; Barton, A.; Medhurst, A.D.; Smith, G.D.; Topp, S.; Sanger, G.; Jenkins, O.; Benham, C.D.; Gloger, I.; Clarke, C. E.; Murdock, P.; Terrett, J.; Randall, A. D.; Gloger, I. S.; Davis, J. B. (2000-11-01)
      Capsaicin, resiniferatoxin, protons or heat have been shown to activate an ion channel, termed the rat vanilloid receptor-1 (rVR1), originally isolated by expression cloning for a capsaicin sensitive phenotype. Here we ...
    • Continuously variable mixing-ratio micromixer with elastomer valves 

      Tan, C. K. L.; Tracey, M.C.; Davis, J. B.; Johnston, I. D. (2005-10)
      We report a self-contained microfluidic alternate flow injection mixer (AFIM) employing piezoelectrically actuated, PDMS seal-valves to control injection. AFIMs employ pulsatile injection of liquids to enhance interface ...
    • Dual independent displacement-amplified micropumps with a single actuator 

      Tracey, M.C.; Johnston, I. D.; Davis, J. B.; Tan, C. K. L. (2006-08)
      We report a dual-micropump structure operated by a single actuator element. The constituent micropumps are a form of micro throttle pump (MTP) comprising a narrow flow channel incorporating two microthrottles. We term this ...
    • Micro throttle pump employing displacement amplification in an elastomeric substrate 

      Johnston, I. D.; Tracey, M.C.; Davis, J. B.; Tan, C. K. L. (2005-10)
      We report a micro throttle pump (MTP) with enhanced throttling resulting from beneficial deformation of its elastomer substrate. In the MTP reported, this has doubled the effective deflection of the piezo electric (PZT) ...
    • Microfluidic solid phase suspension transport with an elastomer-based, single piezo-actuator, micro throttle pump 

      Johnston, I. D.; Tracey, M.C.; Davis, J. B.; Tan, C. K. L. (2005)
      We report a Micro Throttle Pump (MTP) which has been shown to pump 5 mm diameter polystyrene beads at a concentration of 4.5 x 10(7) beads ml(-1). This new MTP design is constructed in a straightforward manner and actuated ...