Browsing University of Hertfordshire by Author "Dhar, Chirag"

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    • Sialoglycan recognition is a common connection linking acidosis, zinc, and HMGB1 in sepsis 

      Siddiqui, Shoib S; Dhar, Chirag; Sundaramurthy, Venkatasubramaniam; Sasmal, Aniruddha; Yu, Hai; Bandala-Sanchez, Esther; Li, Miaomiao; Zhang, Xiaoxiao; Chen, Xi; Harrison, Leonard C; Xu, Ding; Varki, Ajit (2021-03-09)
      Blood pH is tightly maintained between 7.35 and 7.45, and acidosis (pH <7.3) indicates poor prognosis in sepsis, wherein lactic acid from anoxic tissues overwhelms the buffering capacity of blood. Poor sepsis prognosis is ...