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Browsing University of Hertfordshire by Author "Evans, C.R.G."
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Effect of a novel penetration enhancer on the ungual permeation of two antifungal agents
Traynor, M.J.; Turner, R. B.; Evans, C.R.G.; Khengar, R. H.; Jones, S. A.; Brown, Marc (2010-06)Objectives The aim of this study was to demonstrate the effect of a novel permeation enhancer system using two existing marketed nail lacquers and the delivery of terbinafine through human nail samples in vitro. Methods ... -
Overcoming the nail barrier : A systematic investigation of ungual chemical penetration enhancement
Brown, Marc; Khengar, Rajeshree H.; Turner, Rob B.; Forbes, B.; Traynor, M.J.; Evans, C.R.G.; Jones, S. A. (2009-03-31)This study investigated the in vitro nail permeability of penetrants of varying lipophilicity—caffeine (CF, log P −0.07), methylparaben (MP, log P 1.96) and terbinafine (TBF, log P 3.3) and the effect of 2 novel penetration ...