Now showing items 1-6 of 6

    • Clinical and pharmacological properties of ivermectin in rabbits and guinea pigs 

      McKellar, Quintin; Midgley, D. M.; Galbraith, E. A.; Scott, E. W.; Bradley, A. (1992-01)
      When 400 micrograms ivermectin/kg was administered subcutaneously to rabbits infected with the ear mite Psoroptes cuniculi it significantly reduced the clinical score, and when 500 micrograms ivermectin/kg was administered ...
    • Flunixin pharmacokinetics and serum thromboxane inhibition in the dog 

      McKellar, Quintin; Galbraith, E. A.; Bogan, J. A.; Russell, C. S.; Hooke, R. E.; Lees, P. (1989)
      Flunixin meglumine administered orally to beagle dogs at doses of 0.55, 1.10 or 1.65 mg/kg bodyweight was rapidly absorbed to produce maximum mean plasma concentrations of 2.40 +/- 0.70, 4.57 +/- 1.12 and 7.42 +/- 2.07 ...
    • Oral absorption and bioavailability of fenbendazole in the dog and the effect of concurrent ingestion of food 

      McKellar, Quintin; Galbraith, E. A.; Baxter, P. (1993-06)
      Fenbendazole was administered orally without food to six beagle dogs at 2.5, 5.0, 10, 20, 40 and 80 mg/kg of body weight. Increasing the dose rate did not significantly increase the amount of fenbendazole absorbed. In a ...
    • Pharmacokinetics and pharmacodynamics of piroxicam in dogs 

      Galbraith, E. A.; McKellar, Quintin (1991-06)
      Piroxicam was administered to beagle dogs intravenously and orally at a dose rate of 0.3 mg/kg bodyweight. It had an elimination half-life of 40.2 hours, a volume of distribution of 0.29 +/- 0.02 litres/kg and a body ...
    • Pharmacokinetics of fenbendazole in dogs 

      McKellar, Quintin; Harrison, P.; Galbraith, E. A.; Inglis, H. (1990)
      Fenbendazole was administered to dogs at a dose rate of 20 mg/kg body weight on a single occasion in gelatin capsules, on 5 consecutive days in feed, and on a single occasion as an alginate suspension. It was also administered ...
    • Serum thromboxane generation by platelets in several domestic animal species 

      McKellar, Quintin; Nolan, A. M.; Galbraith, E. A. (1990)
      Blood collected from calves, sheep, goats, pigs, dogs, horses, ponies and donkeys, was allowed to clot under standard conditions. Thromboxane B2 generated during the clotting process was measured by radioimmunoassay in ...