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Browsing University of Hertfordshire by Author "Gant, Alex"
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Contractile dysfunction and nitrergic dysregulation in small intestine of a primate model of Parkinson’s disease : contractile dysfunction in MPTP-treated primate ileum
Coletto, E; Dolan, John S; Pritchard, Sara; Gant, Alex; Hikima, Atsuko; Jackson, Michael J; Benham, Christopher; Chaudhuri, K. Ray; Rose, Sarah; Jenner, Peter; Iravani, Mahmoud (2019-06-10)Bowel dysfunction is a common non-motor symptom in Parkinson's disease (PD). The main contractile neurotransmitter in the GI tract is acetylcholine (ACh), while nitric oxide (NO) causes the relaxation of smooth muscle in ... -
Effects of Ketamine and Related New Psychoactive Substances in Rat Urinary Bladder
Gant, Alex (2024-03-28)Introduction: In 2007, Shahani et al. first described the clinical entity of ketamine-induced cystitis (KC) — a condition seen in recreational users of the drug, characterised by the development of various lower urinary ... -
FUNCTIONAL AND HISTOLOGICAL CHANGES IN RAT URINARY BLADDER FOLLOWING SHORT AND LONG TERM KETAMINE EXPOSURE
Gant, Alex; Fergus, Suzanne; Benham, Christopher; Lione, Lisa (2020-11-18)Introduction: Due partly to their dissociative properties, ketamine and related new psychoactive substances (NPS) are widely used as recreational drugs. This has led to the discovery of a link between the chronic use of ...