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Browsing University of Hertfordshire by Author "Johnston, L. C."
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A modified MPTP treatment regime produces reproducible partial nigrostriatal lesions in common marmosets
Iravani, Mahmoud M.; Syed, E.; Jackson, M. J.; Johnston, L. C.; Smith, L. A.; Jenner, P. (2005-02)Standard MPTP treatment regimens in primates result in > 85% destruction of nigral dopaminergic neurons and the onset of marked motor deficits that respond to known symptomatic treatments for Parkinson's disease (PD). The ...