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Browsing University of Hertfordshire by Author "Qian, Wendi"
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Detection of disease change from a biological marker : using CA125 in ovarian cancer as an example
Qian, Wendi; Hall, Marcia; Rustin, Gordon J.; Kornbrot, Diana (2012)Objectives: In Oncology drug development, the great majority of phase 3 trials are negative. New strategies are required to rapidly identify novel agents prior to large randomised trials. The CA125 doubling trial successfully ... -
Detection of disease change using a biological marker and clinical application: CA125 in ovarian cancer patients
Qian, Wendi; Hall, Marcia; Rustin, Gordon J.; Kornbrot, Diana (2012)In Oncology drug development, the great majority of phase 3 trials are negative.. New strategies are required to rapidly identify novel agents prior to large randomised trials. The CA125 doubling trial successfully showed ... -
Using serum CA125 to assess the activity of potential cytostatic agents in ovarian cancer
Hall, M.R.; Petruckevitch, A.; Pascoe, Joanna; Persic, Mojca; Tahir, Saad; Morgan, J.S.; Gourley, Charlie; Stuart, N.S.A.; Crawford, S.M.; Kornbrot, D.E.; Qian, Wendi; Rustin, G.J.S. (2014-05)Objective: New strategies are required to rapidly identify novel cytostatic agents before embarking on large randomized trials. This study investigates whether a change in rate of rise (slope) of serum CA125 from before ...